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US 10,517,869 B2Granted
Topical brimonidine tartrate ophthalmic solution
AssigneeSentiss Pharma Private Limited
InventorsMandar V. Shah, Deepak Bahri
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Abstract
The present invention provides an aqueous ophthalmic composition comprising an alpha-2 adrenergic receptor agonist and a non-ionic cellulosic polymer, the solution having a pH less than 6.5. The present invention also provides an aqueous ophthalmic composition comprising an alpha-2 adrenergic receptor agonist and a benzododecinium halide. Also provided are methods of manufacture, use and method of reducing intraocular pressure in the patient in need thereof.
Claims2
An aqueous ophthalmic composition comprising
- a) brimonidine tartrate in an amount of 0.01-0.5% (w/v);
- b) hydroxypropyl methylcellulose in an amount of 0.1-1.0% (w/v);
- and
- c) benzododecinium halide in an amount of 0.001% to 0.1% (w/v) which is devoid of anionic cellulosic polymer, wherein the pH of said composition is less than 6.5.
1 more element
Dependencies are inferred from the claim text.