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US 10,517,817 B2Granted
Deep topical systemic nitric oxide therapy apparatus and method
AssigneeSyk Technologies, LLC
InventorsChristian S. Minton, Stephen D. Minton, J. W. Randolph Miller
Life of this patent
Estimating the term…
Abstract
A topical mixture that produces nitric oxide and a method for using the topical mixture to increase the vasodilation of a bloodstream via transdermal absorption of the nitric oxide. The nitric oxide can then affect subcutaneous tissues. The systemic vasodilation of a mammal may be increased via a topical application of an appropriate nitric oxide producing substance.
Claims19
A method for increasing vasodilation comprising:
- providing a mammal with an epidermal surface and a bloodstream having an initial systemic vasodilation of the bloodstream;
- providing a first medium comprising a nitrite compound;
- providing a second medium comprising at least two reducing agents;
- creating a mixture of the first medium and the second medium thereby initiating production of nitric oxide;
- applying the mixture onto the epidermal surface of the mammal;
- absorbing at least 500 ppm of nitric oxide transdermally within 10 minutes after the applying;
- and
- increasing the systemic vasodilation of the bloodstream of the mammal as compared to the initial vasodilation.
5 more elements
A method for treating systemic hemodynamic disorders comprising:
- providing a mammal with an epidermal surface and a bloodstream having a systemic hemodynamic disorder;
- providing a first medium comprising a nitrite compound and sodium bicarbonate;
- providing a second medium comprising a reducing agent;
- creating a mixture of the first medium and the second medium thereby initiating production of nitric oxide;
- applying the mixture onto the epidermal surface of the mammal;
- and
- increasing systemic vasodilation of the bloodstream of the mammal to treat the systemic hemodynamic disorder.
4 more elements
A method for increasing vasodilation comprising:
- providing a mammal with an epidermal surface and a bloodstream having an initial systemic vasodilation of the bloodstream;
- providing a first medium comprising a nitrite compound;
- providing a second medium comprising at least two reducing agents;
- creating a mixture of the first medium and the second medium thereby initiating production of nitric oxide, wherein the mixture also includes a salt buffer for prolonging the production of nitric oxide, wherein the salt used in the salt buffer includes at least one salt selected from a group consisting of sodium chloride and calcium chloride;
- applying the mixture onto the epidermal surface of the mammal;
- absorbing an effective amount of nitric oxide transdermally;
- and
- increasing the systemic vasodilation of the bloodstream of the mammal as compared to the initial vasodilation.
5 more elements
Dependencies are inferred from the claim text.