Heart valve sealing devices and delivery devices therefor

An assembly, comprising:

• an implantable prosthetic device having a spacer body, an end member axially spaced from and axially movable relative to the spacer body, and a plurality of anchor each comprising a braided material, wherein the spacer body has a first end portion, a second end portion, and a longitudinal axis extending from the first end portion to the second end portion, wherein the spacer body is configured to restrict antegrade blood flow through the spacer body from the first end portion to the second end portion and to restrict retrograde blood flow through the spacer body from the second end portion to the first end portion, wherein first end portions of the anchors are coupled to second end portion of the spacer body, and wherein second end portions of the anchors are coupled to the end member;
• and
• a delivery apparatus having a first shaft and a second shaft, wherein the first shaft and the second shaft are moveable relative to each other,
• wherein the end member is releasably coupled to the first shaft, and the first end portion of the spacer body is releasably coupled to the second shaft,
• wherein the delivery apparatus is configured such that moving the first shaft and the second shaft relative to each moves the prosthetic device between a first configuration, in which the spacer body is radially compressed and is longitudinally spaced relative to the anchors, and a second configuration, in which the spacer body expands radially outwardly relative to the first configuration and the anchors at least partially overlap the spacer body to capture native leaflets between the anchors and the spacer body.

A method of implanting a prosthetic device, comprising:

• advancing a prosthetic device in a compressed configuration to an implantation location using a delivery apparatus, wherein the prosthetic device comprises a spacer body, an end member, a first anchor, and a second anchor, each anchor comprising a braided material, wherein the spacer body has a first end portion, a second end portion, and a longitudinal axis extending from the first end portion to the second end portion, wherein the spacer body is configured to restrict antegrade blood flow through the spacer body from the first end portion to the second end portion and to restrict retrograde blood flow through the spacer body from the second end portion to the first end portion, wherein the end member is longitudinally spaced from and longitudinally movable relative to the spacer body, and wherein the first anchor and the second anchor each comprise a first end portion coupled to the second end portion of the spacer body and a second end portion coupled to the end member;
• radially expanding the prosthetic device from the compressed configuration to an expanded configuration by actuating the delivery apparatus to move the spacer body longitudinally relative to the end member;
• capturing a first native leaflet against the first anchor by actuating the delivery apparatus;
• capturing a second native leaflet against the second anchor by actuating the delivery apparatus;
• securing the first native leaflet and the second native leaflet against the spacer body of the prosthetic device by actuating the delivery apparatus to move the first anchor and the second anchor relative to the spacer body so that each anchor at least partially overlaps the spacer body;
• and
• releasing the prosthetic device from the delivery apparatus.