Systems and methods for mechanical mapping of cardiac rhythm
AssigneeThe Trustees of Columbia University in the City of New York
InventorsElisa E. Konofagou, Jean Provost, Alok Gambhir, Alexandre Costet, Elaine Wan, Julien Grondin
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Abstract
Techniques for mapping behavior of a heart include acquiring a series of two or more images of the heart. The series of images is taken at one or more pixel locations, each pixel location corresponding to a region of the heart. Image data corresponding to the pixel locations can be obtained, and a periodicity of the image data measured for each of the pixel locations over the series of images. The periodicity corresponds to an electromechanical signal of the heart in the region corresponding to the measured one or more pixel locations.
Claims31
An imaging system for mapping behavior of a heart, comprising:
- an imaging device configured to acquire a series of two or more images of the heart over a period at one or more pixel locations, each pixel location corresponding to a region of the heart;
- and
- an image processor, coupled to the imaging device, configured to:
- obtain image data of the one or more pixel locations during the-period,
- measure a periodicity of the image data for each of the one or more pixel locations over the series of images, wherein the periodicity corresponds to an electromechanical signal of the heart in the region corresponding to the measured one or more pixel locations, and
- analyze the electromechanical signal to determine one or more patterns characteristic of an arrhythmia,
- determine a source or a type of the arrhythmia based on the one or more patterns determined from the electromechanical signal, wherein the arrhythmia comprises at least one of a focal arrhythmia, a reentrant arrhythmia, and atrial flutter, and
- if the one or more patterns determined from the electromechanical signal indicates the arrhythmia is the focal arrhythmia, identifying a location of a focal zone and a subsequent propagation of cardiac activation;
- if the one or more patterns determined from the electromechanical signal indicates the arrhythmia is the reentrant arrhythmia, perform a Fourier analysis on the electromechanical signal to determine a cycle length and one or more propagation patterns;
- and
- if the one or more patterns determined from the electromechanical signal indicates the atrial flutter, analyze strain images of the heart to identify an anatomic structure and guide ablation to treat the arrhythmia.
A method for planning and monitoring treatment of an arrhythmia in a heart, comprising:
- acquiring a series of two or more images of the heart over a period, the series of images taken at one or more pixel locations, each pixel location corresponding to a region of the heart;
- obtaining image data corresponding to the one or more pixel locations during the period;
- measuring, by an image processor, a periodicity of the image data for each of the one or more pixel locations over the series of images, wherein the periodicity corresponds to an electromechanical signal of the heart in the region corresponding to the measured one or more pixel locations;
- analyzing the electromechanical signal to determine one or more patterns characteristic of the arrhythmia;
- determining a source or a type of the arrhythmia based on the one or more patterns determined from the electromechanical signal, wherein the arrhythmia comprises at least one of a focal arrhythmia, a reentrant arrhythmia, and atrial flutter, and
- if the one or more patterns determined from the electromechanical signal indicates the arrhythmia is the focal arrhythmia, identifying a location of a focal zone and a subsequent propagation of cardiac activation;
- if the one or more patterns determined from the electromechanical signal indicates the arrhythmia is the reentrant arrhythmia, performing a Fourier analysis on the electromechanical signal to determine a cycle length and one or more propagation patterns;
- and
- if the one or more patterns determined from the electromechanical signal indicates the atrial flutter, imaging the heart to identify an anatomic structure and guide ablation to treat the arrhythmia.
Dependencies are inferred from the claim text.