# US 10,502,724 B2 · Ultra-low power digital chemical analyzers > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,502,724 B2 - Document ID: US10502724B2 - Status: Granted - Kind: B2 - Application number: 15/376,562 - Filed: 2016-12-12 - Published: 2018-08-16 - Granted: 2019-12-10 - Earliest claimed: 2015-10-13 - Assignees: University of Utah Research Foundation - Applicants: University of Utah Research Foundation - Inventors: Hanseup Kim; Carlos Mastrangelo - Web page: https://patentgrep.com/patent/US10502724B2 ## CPC - G01N 33/0057: {Warfare agents or explosives} - A62D 3/11: Electrochemical processes, e.g. electrodialysis - B01D 46/0032: {using electrostatic forces to remove particles, e.g. electret filters} - G01N 27/021: {before and after chemical transformation of the material} - G01N 33/0063: {using a threshold to release an alarm or displaying means} - B01L 2300/0645: Electrodes - B82Y 15/00: Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors - B82Y 40/00: Manufacture or treatment of nanostructures - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) - A62D: CHEMICAL MEANS FOR EXTINGUISHING FIRES OR FOR COMBATING OR PROTECTING AGAINST HARMFUL CHEMICAL AGENTS; CHEMICAL MATERIALS FOR USE IN BREATHING APPARATUS - B01D: SEPARATION (separating solids from solids by wet methods B03B, B03D; by pneumatic jigs or tables B03B; by other dry methods B07; magnetic or electrostatic separation of solid materials from solid materials or fluids, separation by high-voltage electric fields B03C; centrifuges, vortex apparatus B04; presses per se for squeezing-out liquid from liquid-containing material B30B9/02; treatment of water C02F, e.g. softening by ion-exchange C02F1/42; {arrangements of air intake cleaners in gas turbine plants F02C7/05} ; arrangements or mounting of filters in air-conditioning, air-humidification or ventilation F24F13/28) - B01L: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE - B82Y: SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES ## Abstract A zero-power digital chemical analyzer can include a chemically-selective percolation switch. The chemically selected percolation switch can include a positive electrode and a negative electrode separated from the positive electrode by a gap. A binding agent can be located at binding sites in the gap. The binding agent can be selective for binding to a target chemical compound. The binding sites can be distributed in the gap so that target chemical molecules binding to the binding sites can form an electrically conductive pathway via a natural percolation phenomenon between the electrodes when the ambient concentration of the target chemical compound reaches a threshold concentration. ## Claims ### Claim 1 A chemically-selective percolation switch, comprising: a positive electrode; a negative electrode separated from the positive electrode by a horizontal switch gap; a plurality of electrically conductive horizontal parallel plates formed in the switch gap, wherein at least some of the horizontal parallel plates vertically overlap at least some other horizontal parallel plates to form vertical structure gaps; and a binding agent located at a plurality of binding sites in the switch gap, wherein the binding agent is selective for binding to a target chemical compound, wherein the binding sites are on horizontal surfaces of the horizontal parallel plates, wherein the binding sites are distributed in the switch gap such that the binding sites are capable of binding molecules of the target chemical compound to form an electrically conductive pathway via percolation between the positive electrode and the negative electrode when the chemically-selective percolation switch is exposed to a threshold concentration of the target chemical compound. ### Claim 2 (depends on 1) The chemically-selective percolation switch of claim 1, wherein the threshold concentration can be adjusted from 1 part per billion (ppb) to 1000 part per million (ppm). ### Claim 3 (depends on 1) The chemically-selective percolation switch of claim 1, wherein the target chemical compound is a chemical warfare agent, an air pollutant, an airborne compound, a fuel, an explosive, an airborne biological agent, or combinations thereof. ### Claim 4 (depends on 1) The chemically-selective percolation switch of claim 1, wherein the horizontal parallel plates have a shape selected from circular, hexagonal, square, rectangular, and triangular. ### Claim 5 (depends on 1) The chemically-selective percolation switch of claim 1, wherein the horizontal parallel plates have a width from 1 micrometer to 1 millimeter. ### Claim 6 (depends on 1) The chemically-selective percolation switch of claim 1, wherein the vertical structure gaps have a structure gap distance from 0.3 nanometer to 100 micrometers. ### Claim 7 (depends on 1) The chemically-selective percolation switch of claim 1, further comprising a power supply connected to the positive electrode and the negative electrode to apply a bias voltage to the positive electrode and the negative electrode. ### Claim 8 (depends on 1) The chemically-selective percolation switch of claim 1, wherein the binding agent comprises a selective binding material. ### Claim 9 (depends on 1) The chemically-selective percolation switch of claim 1, wherein the plurality of electrically conductive horizontal parallel plates includes a first layer of horizontal plates in a same plane as the positive electrode and a second layer of horizontal plates in a same plane as the negative electrode, wherein the horizontal plates of the first layer vertically overlap the horizontal plates of the second layer. ### Claim 10 (depends on 1) The chemically-selective percolation switch of claim 1, wherein the plurality of electrically conductive horizontal parallel plates includes square plates vertically overlapping at corners of the square plates. ### Claim 11 (depends on 1) The chemically-selective percolation switch of claim 1, wherein the plurality of electrically conductive horizontal parallel plates includes a first layer of circular plates and a second layer of triangular plates, wherein the circulate plates vertically overlap the triangular plates at corners of the triangular plates. ### Claim 12 (depends on 1) The chemically-selective percolation switch of claim 1, wherein the plurality of electrically conductive horizontal parallel plates are organized as a linear row of vertically overlapping horizontal parallel plates. ### Claim 13 A zero-power digital chemical analyzer, comprising: a power supply; a detection circuit; and a chemically-selective percolation switch electrically connected between the power supply and the detection circuit, wherein the chemically-selective percolation switch is configured to switch the detection circuit to an on state when the chemically-selective percolation switch is exposed to a threshold concentration of a target chemical compound, and wherein the chemically-selective percolation switch comprises: a positive electrode; a negative electrode separated from the positive electrode by a horizontal switch gap; a plurality of electrically conductive horizontal parallel plates formed in the switch gap, wherein at least some of the horizontal parallel plates vertically overlap at least some other horizontal parallel plates to form vertical structure gaps; and a binding agent located at a plurality of binding sites in the switch gap, wherein the binding agent is selective for binding to the target chemical compound, wherein the binding sites are on horizontal surfaces of the horizontal parallel plates, wherein the binding sites are distributed in the switch gap such that the binding sites are capable of binding molecules of the target chemical compound to form an electrically conductive pathway via percolation between the positive electrode and the negative electrode when the chemically-selective percolation switch is exposed to the threshold concentration of the target chemical compound. ### Claim 14 (depends on 13) The zero-power digital chemical analyzer of claim 13, further comprising a charging capacitor electrically connected between the chemically-selective percolation switch and the detection circuit. ### Claim 15 (depends on 13) The zero-power digital chemical analyzer of claim 13, wherein the chemically-selective percolation switch conducts a trivial current of less than 1 pA when the chemically-selective percolation switch is exposed to a concentration of the target chemical compound below the threshold concentration, and conducts a significant amount of current of at least 1 nA when the chemically-selective percolation switch is exposed to the threshold concentration of the target chemical compound, forming an electrically-conductive path via the natural percolation phenomenon. ### Claim 16 (depends on 13) The zero-power digital chemical analyzer of claim 13, further comprising a second chemically-selective percolation switch connected in series with the chemically-selective percolation switch so that the detection circuit is not switched to the on state unless both the chemically-selective percolation switch and the second chemically-selective percolation switch conduct electric current from the power supply, wherein the second chemically-selective percolation switch is tuned to conduct electricity via the natural percolation phenomenon when exposed to the same threshold concentration of the target chemical compound as the chemically-selective percolation switch. ### Claim 17 (depends on 13) The zero-power digital chemical analyzer of claim 13, further comprising a second chemically-selective percolation switch connected in series with the chemically-selective percolation switch and an additional pair of chemically-selective percolation switches connected in parallel one with another, wherein the additional pair of chemically-selective percolation switches is connected in series with the first and second chemically selective percolation switches to form an XOR logic gate. ### Claim 18 A digital chemical analyzer, comprising: a power supply; a first chemically-selective percolation switch tuned to conduct electric current from the power supply when exposed to a first threshold concentration of a target chemical compound; and a second chemically-selective percolation switch tuned to conduct electric current when exposed to a second threshold concentration of the target chemical compound, wherein the second threshold concentration is greater than the first threshold concentration; wherein the first and second chemically-selective percolation switches each comprise: a positive electrode; a negative electrode separated from the positive electrode by a horizontal switch gap; a plurality of electrically conductive horizontal parallel plates formed in the switch gap, wherein at least some of the horizontal parallel plates vertically overlap at least some other horizontal parallel plates to form vertical structure gaps; and a binding agent located at a plurality of binding sites in the switch gap, wherein the binding agent is selective for binding to the target chemical compound, wherein the binding sites are on horizontal surfaces of the horizontal parallel plates, wherein the binding sites are distributed in the switch gap such that the binding sites are capable of binding molecules of the target chemical compound to form an electrically conductive pathway via percolation between the positive electrode and the negative electrode when the chemically-selective percolation switch is exposed to the threshold concentration of the target chemical compound. ### Claim 19 (depends on 18) The digital chemical analyzer of claim 18, further comprising a detection circuit electrically connected to the first and second chemically-selective percolation switches, wherein the detection circuit is configured to determine a minimum ambient concentration of the target chemical compound based on signals from the first and second chemically-selective percolation switches. ### Claim 20 (depends on 18) The digital chemical analyzer of claim 18, wherein the first and second chemically-selective percolation switches are tuned to the first and second threshold concentrations by adjusting one or more of a bias voltage, binding agent, binding agent concentration, switch gap distance between electrodes, distance between electrically conductive structures in the switch gap, surface area of electrically conductive structures in the switch gap, height of electrically conductive structures in the switch gap, or combinations thereof.