# US 10,502,667 B2 · Apparatuses for generating a reciprocating motion for the purpose of grinding of samples > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,502,667 B2 - Document ID: US10502667B2 - Status: Granted - Kind: B2 - Application number: 15/702,612 - Filed: 2017-09-12 - Published: 2018-04-05 - Granted: 2019-12-10 - Earliest claimed: 2013-04-25 - Assignees: Rotaprep, Inc. - Applicants: Rotaprep, Inc. - Inventors: Horacio Kido - Web page: https://patentgrep.com/patent/US10502667B2 ## CPC - G01N 1/286: {involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising (microtomes G01N1/06; pulverising in general B02C; mixing in general B01F)} - B01F 31/201: {Holders therefor} - B01F 31/22: with supporting means moving in a horizontal plane, e.g. describing an orbital path for moving the containers about an axis which intersects the receptacle axis at an angle - B01F 33/251: {using balls as loose mixing element} - B01F 33/50115: {Stirring devices adapted to be connected to a standard boring machine or other kind of domestic tool} - B02C 17/00: Disintegrating by tumbling mills, i.e. mills having a container charged with the material to be disintegrated with or without special disintegrating members such as pebbles or balls (high-speed drum mills B02C19/11 {; drums for polishing or grinding B24B}) - B02C 17/14: Mills in which the charge to be ground is turned over by movements of the container other than by rotating, e.g. by swinging, vibrating, tilting {(mills provided with vibrators in general B02C19/16)} - B02C 17/24: Driving mechanisms - G01N 2001/2866: {Grinding or homogeneising} - Y10T 29/49826: Assembling or joining - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) - B01F: MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING (mixing paints B44D3/06) - B02C: CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN ({household tools and machines for pulverising foodstuffs, e.g. coffee and spice mills A47J42/00; pharmaceutical mortars A61J3/02; mechanical processing of refuse and garbage B03B9/06; dressing mould materials by grinding B22C5/04}; obtaining metallic powder by crushing, grinding or milling B22F9/04; {recovery of plastics by disintegrating B29B17/00; crushing raw materials in starch making C08B30/02; beaters for papermaking D21D1/02; crushing devices specially for transport in mines E21F13/002; slag crushing devices F23J1/00; fuel milling devices in combustion apparatus F23K1/00; household devices for crushing coal F24B15/02; ice disintegrating devices F25C5/02}) - Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION ## Abstract Disclosed herein are devices, apparatuses, and methods for generating a reciprocating motion for the purpose of grinding or homogenizing samples. An apparatus includes a connecting linkage that extends along a longitudinal axis. The apparatus includes a sample vial holder attached to the connecting linkage. The apparatus includes a crank operatively connected to the proximal end of the connecting linkage, the crank configured to impart rotational motion to the proximal end of the connecting linkage. The apparatus includes a sliding carriage operatively connected to the distal end of the connecting linkage, the sliding carriage configured to restrict the distal end of the connecting linkage to a linear path. The apparatus includes a motor operatively connected to the crank to rotate the crank such that the sample vial holder, in use, moves with a combination of rotational and linear motion. ## Claims ### Claim 1 An apparatus generating a reciprocating motion for the purpose of grinding or homogenizing samples, the apparatus comprising: a connecting linkage having a proximal end and a distal end, the connecting linkage extending along a longitudinal axis between the proximal end and the distal end; a holder, to hold a sample vial, attached to the connecting linkage between the proximal end and the distal end along the longitudinal axis of the connecting linkage, the holder forming a cavity having a cavity axial length that is configured to secure the sample vial; a crank operatively connected to the proximal end of the connecting linkage, the crank configured to impart rotational motion to the proximal end of the connecting linkage, wherein the crank has a diameter that is greater than or equal to the cavity axial length; a sliding carriage operatively connected to the distal end of the connecting linkage, the sliding carriage configured to restrict the distal end of the connecting linkage to a linear path; and a motor operatively connected to the crank to rotate the crank such that the holder, in use, moves with a combination of rotational and linear motion. ### Claim 2 (depends on 1) The apparatus of claim 1 wherein the cavity axial length is less than or equal to 1.5 inches. ### Claim 3 (depends on 1) The apparatus of claim 1 wherein the holder attachment onto the connecting linkage is adjustable such that the holder is configured to be relocated along the longitudinal axis of the connecting linkage. ### Claim 4 (depends on 1) The apparatus of claim 1 wherein the holder moves in an elliptical path in use, the elliptical path having a major axis that is greater than or equal to the cavity axial length. ### Claim 5 (depends on 1) The apparatus of claim 1 wherein the connecting linkage is less than or equal to 7.3 inches long. ### Claim 6 (depends on 1) The apparatus of claim 1 wherein, in use, the motor is configured to cause the holder to experience a reciprocation rate of between 4,000 and 5,000 cycles per minute. ### Claim 7 An apparatus generating a reciprocating motion for the purpose of grinding or homogenizing samples, the apparatus comprising: a connecting linkage having a proximal end and a distal end; a crank configured to rotate about a central axis; a crank pivot coupled to the crank at a position away from the central axis of the crank and coupled to the connecting linkage at the proximal end of the connecting linkage such that as the crank rotates the proximal end of the connecting linkage undergoes rotational motion; a sliding carriage configured to slide along a rail; a slide pivot coupled to the sliding carriage and coupled to the connecting linkage at the distal end of the connecting linkage such that as the crank rotates the distal end of the connecting linkage undergoes linear motion; a holder configured to hold a sample vial, the holder attached to the connecting linkage between the proximal end and the distal end such that as the crank rotates the sample vial undergoes a combination of rotational and linear motion. ### Claim 8 (depends on 7) The apparatus of claim 7 wherein the holder forms a cavity to secure the sample vial as the holder undergoes the combination of rotational and linear motion. ### Claim 9 (depends on 7) The apparatus of claim 7 further comprising a second holder coupled to the connecting linkage. ### Claim 10 (depends on 7) The apparatus of claim 7 wherein the holder is configured to hold a plurality of sample vials. ### Claim 11 (depends on 10) The apparatus of claim 10 wherein the holder forms a plurality of cavities to secure the corresponding plurality of sample vials. ### Claim 12 A mechanical reciprocating apparatus to grind or homogenize samples, the apparatus comprising: a holder configured to hold a sample vial; a connecting linkage having a proximal pivot point and a distal pivot point, the holder being attached to the connecting linkage between the proximal pivot point and the distal pivot point; a frame top; a rail coupled to the frame top; a crank pivot connected to the proximal pivot point of the connecting linkage; a slide pivot connected to the distal pivot point of the connecting linkage; a sliding carriage coupled to the slide pivot and to the rail such that the sliding carriage is configured to slide along the rail thereby causing the slide pivot to undergo linear motion; and a crank attached to the crank pivot and positioned between the connecting linkage and the frame top. ### Claim 13 (depends on 12) The apparatus of claim 12 wherein the connecting linkage is configured to accommodate multiple holders. ### Claim 14 (depends on 12) The apparatus of claim 12 further comprising a frame bottom coupled to the frame top using one or more spacers to maintain the frame bottom a fixed distance from the frame top. ### Claim 15 (depends on 14) The apparatus of claim 14 further comprising: a small pully positioned between the frame top and the frame bottom; a small pulley shaft operatively coupled to the small pully such that rotation of the small pulley shaft causes the small pully to rotate; a big pully positioned between the frame top and the frame bottom; a big pully shaft coupled to the big pully and to the crank such that rotation of the big pully causes the crank to rotate by way of the big pully shaft; and a drive belt coupled to the big pully and to the small pully wherein rotation of the small pully causes the big pully to rotate by way of the drive belt. ### Claim 16 (depends on 15) The apparatus of claim 15 further comprising a threaded adapter coupled to the frame bottom and configured to couple to a motor to provide an operative coupling between the small pulley and the motor so that rotation of the motor causes rotation of the small pulley by way of the small pully shaft. ### Claim 17 (depends on 12) The apparatus of claim 12 wherein the holder forms a cavity having a cavity axial length that is configured to secure a sample vial. ### Claim 18 (depends on 17) The apparatus of claim 17 wherein a diameter of rotational motion of the crank pivot is greater than or equal to the cavity axial length. ### Claim 19 (depends on 17) The apparatus of claim 17 wherein at least a portion of the holder is configured to move in an elliptical path that has a major axis that is greater than or equal to the cavity axial length. ### Claim 20 (depends on 12) The apparatus of claim 12 wherein the holder is configured to be attached at a plurality of locations on the connecting linkage to adjust the characteristics of motion of the holder.