# US 10,501,776 B2 · Sorbents for the extraction and stabilization of nucleic acids

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 10,501,776 B2
- Document ID: US10501776B2
- Status: Granted
- Kind: B2
- Application number: 16/106,066
- Filed: 2018-08-21
- Published: 2019-01-17
- Granted: 2019-12-10
- Earliest claimed: 2016-09-13
- Assignees: The Government of the United States of America, as represented by the Secretary of the Navy
- Applicants: The Government of the United States of America, as represented by the Secretary of the Navy
- Inventors: Baochuan Lin; Brandy J. White; Brian Melde
- Web page: https://patentgrep.com/patent/US10501776B2

## CPC

- C12Q 1/6806: Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay (C12Q1/6804 takes precedence)
- C12Q: MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS (immunoassay G01N33/53); COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES

## Abstract

Mesoporous sorbents are effective for storing and transporting nucleic acids. In particular, two ethane-bridged silica sorbents with amine functionalities are particularly effective and capable of binding nucleic acids for storage.

## Claims

### Claim 1

A nucleic acid sorbent comprising a mesoporous ethane-bridged silica and both N5 and CuEDA.

### Claim 2 (depends on 1)

The nucleic acid sorbent of claim 1, in a condition of having been washed with a detergent.

### Claim 3 (depends on 1)

The nucleic acid sorbent of claim 1, further comprising a nucleic acid in complex with the sorbent.

### Claim 4 (depends on 1)

The nucleic acid sorbent of claim 1, in a condition of being associated with a stabilizer.

### Claim 5 (depends on 4)

The nucleic acid sorbent of claim 4, wherein said stabilizer is selected from the group consisting of bovine serum albumin, trehalose, and glucosamine.