# US 10,501,383 B2 · Nitrification inhibitor compositions and methods of making thereof > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,501,383 B2 - Document ID: US10501383B2 - Status: Granted - Kind: B2 - Application number: 15/521,752 - Filed: 2015-11-02 - Published: 2017-09-07 - Granted: 2019-12-10 - Earliest claimed: 2014-10-31 - Assignees: Koch Agronomic Services, LLC - Applicants: Koch Agronomic Services, LLC - Inventors: Kurt Gabrielson; Stacey Wertz; Drew Bobeck; Allen Sutton - Web page: https://patentgrep.com/patent/US10501383B2 ## CPC - C05C 9/005: {Post-treatment} - C05C 9/02: containing urea-formaldehyde condensates - C05G 3/90: for affecting the nitrification of ammonium compounds or urea in the soil - C05G 5/12: Granules or flakes - Y02P 60/21: Dinitrogen oxide [N2O], e.g. using aquaponics, hydroponics or efficiency measures - C05C: NITROGENOUS FERTILISERS - C05G: MIXTURES OF FERTILISERS COVERED INDIVIDUALLY BY DIFFERENT SUBCLASSES OF CLASS C05; MIXTURES OF ONE OR MORE FERTILISERS WITH MATERIALS NOT HAVING A SPECIFIC FERTILISING ACTIVITY, e.g. PESTICIDES, SOIL-CONDITIONERS, WETTING AGENTS (organic fertilisers containing added bacterial cultures, mycelia, or the like C05F11/08; organic fertilisers containing plant vitamins or hormones C05F11/10); FERTILISERS CHARACTERISED BY THEIR FORM - Y02P: CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS ## Abstract An improved nitrification inhibitor composition comprising UFP particles and a nitrification inhibitor, and optionally other components, is used as an additive for liquid and solid fertilizers, typically containing urea. The nitrification inhibitor particularly can be nitrapyrin and/or DMPP. Methods of making the compositions and their use are also disclosed. ## Claims ### Claim 1 A composition comprising components: (a) a nitrification inhibitor selected from the group consisting of 2-chloro-6-trichloromethylpyridine (nitrapyrin), 3,4-dimethylpyrazole phosphate (DMPP), 3-methylpyrazole (MP); 1-H-1,2,4-triazole (TZ); 3-methylpyrazole-1-carboxamide (CMP); 4-amino-1,2,4-triazole (AT, ATC); 3-amino-1,2,4-triazole; 2-cyanimino-4-hydroxy-6-methylpyrimidine (CP); 2-ethylpyridine; ammonium thiosulfate (ATS); sodium thiosulfate (ST); thiophosphoryl triamide; thiourea (TU); guanylthiourea (GTU); ammonium polycarboxilate; ethylene urea; hydroquinone; 10 phenylacetylene; phenylphosphoro diamidate; neemcake; calcium carbide; 5-ethoxy-3-trichloromethyl-1,2,4-thiadiazol (etridiazol; terraole); 2-amino-4-chloro-6-methylpyrimidine (AM); 1-mercapto-1,2,4-triazole (MT); 2-mercaptobenzothiazole (MBT); 2-sulfanilamidothiazole (ST); 5-amino-1,2,4-thiadiazole; 2,4-diamino-6-trichloromethyl-s-triazine (CL-1580); N-2,5-dichlorophenyl succinanilic acid (DCS); nitroaniline, chloroaniline, and salts thereof; and (b) urea-formaldehyde polymer (UFP) particles; wherein the composition comprises about 30% by weight to about 95% by weight of the nitrification inhibitor. ### Claim 2 (depends on 1) The composition of claim 1, wherein the nitrification inhibitor is dimethylpyrazole phosphate (DMPP). ### Claim 3 (depends on 1) The composition of claim 1, wherein the nitrification inhibitor is nitrapyrin. ### Claim 4 (depends on 3) The composition of claim 3, further comprising a urease inhibitor. ### Claim 5 (depends on 4) The composition of claim 4, wherein the urease inhibitor is N-(n-butyl)thiophosphoric triamide (NBPT). ### Claim 6 (depends on 4) The composition of claim 4, wherein composition comprises about 15% by weight to about 40% by weight of the urease inhibitor, about 15% by weight to about 50% by weight of the UFP particles, and about 40% by weight to about 95% by weight of the nitrification inhibitor, based on the total weight of the composition. ### Claim 7 (depends on 1) The composition of claim 1, further comprising one or more components selected from the group consisting of a conditioner, a pigment, and a dye. ### Claim 8 (depends on 7) A composition according to claim 7, wherein the composition comprises a conditioner selected from the group consisting of mineral oil, tricalcium phosphate, sodium bicarbonate, sodium ferricyanide, potassium ferricyanide, bone phosphate, sodium silicate, silicon dioxide, calcium silicate, talcum powder, bentonite, calcium aluminum silicate, stearic acid, sodium aluminosilicate, and polyacrylate powder. ### Claim 9 (depends on 1) A composition of claim 1, wherein at least one of the following conditions is met: a majority of the UFP particles have a particle diameter in the range of about 150 μm to about 10 μm; the UFP particles have an average diameter of about 0.05 microns to about 250 microns; the UFP particles have an average diameter of about 0.1 microns to about 150 microns; at least a portion of the UFP particles have an average diameter of about 0.01 microns to about 50 microns; about 0.1% to about 50% by weight of the UFP particles have an average diameter of about 0.05 microns to about 5 microns; about 5% to about 99% by weight of the UFP particles have an average diameter of about 10 microns to about 150 microns; about 0.1% by weight to about 40% by weight of the UFP particles have an average diameter that is up to a threshold value, and about 50% by weight to about 99% by weight of the particles have an average diameter that is greater than the threshold value, said threshold value being 0.5 microns, 1 micron, 2 microns, 5 microns, or 10 microns. ### Claim 10 (depends on 9) The composition of claim 9, wherein the UFP particles are substantially spherical. ### Claim 11 (depends on 10) The composition of claim 10, wherein the substantially spherical UFP particles are made by acidifying an aqueous methylol urea solution, wherein the aqueous methylol urea solution is made by reacting urea and formaldehyde at a urea:formaldehyde mole ratio of from 0.7:1 to 1.25:1, and wherein the aqueous methylol urea solution contains a dispersing agent, is subjected to a high shear condition during the acidifying, or both contains a dispersing agent and is subjected to a high shear condition during the acidifying, to form an aqueous dispersion of insoluble urea formaldehyde polymer particles and drying the dispersion to recover the urea-formaldehyde polymer particles. ### Claim 12 (depends on 1) The composition of claim 1, wherein the composition is made by a process comprising contacting the UFP particles with a solution of said nitrification inhibitor in a solvent under conditions including elevated temperatures and sub-atmospheric pressures thereby forming said composition. ### Claim 13 (depends on 12) The composition of claim 12, wherein the solvent is selected from the group consisting of NMP, polyethylene glycol, THP, propylene glycol, ethylene glycol, Solketal, glycerol, glycol derivatives, ethyl acetate dibasic esters, triethanolamine, alkanolamines, methylene chloride, solvent naptha, xylenes, benzene, toluene, DMSO, and other sulfoxide derivatives, dibasic ester derivatives, acetone, glycol ethers, polyalkyleneglycol ethers, benzyl alcohol, propylene carbonate, ethylene carbonate, dioxane, hexanes, heptane, and combinations thereof. ### Claim 14 (depends on 1) The composition of claim 1, comprising about 30% by weight to about 95% by weight of the nitrification inhibitor and about 5% by weight to about 70% by weight of the UFP particles based on the total weight of the composition. ### Claim 15 (depends on 1) A fertilizer comprising urea and the composition of claim 1 wherein said urea is present in an amount of about 90% by weight to about 99% by weight and the content of said nitrification inhibitor and said UFP particles is present in an amount of about 0.02% by weight to about 0.5% by weight. ### Claim 16 (depends on 15) The fertilizer of claim 15, wherein the fertilizer is in a granule, a prill, a pellet, a pastille, or a compounded form. ### Claim 17 (depends on 16) The fertilizer of claim 16, wherein the fertilizer is a granule having a diameter of about 0.8 mm to about 4.8 mm. ### Claim 18 (depends on 15) The fertilizer of claim 15, wherein the composition further comprises a urease inhibitor. ### Claim 19 (depends on 15) The fertilizer of claim 15, wherein the composition further comprises one or more components selected from the group consisting of a conditioner, a pigment, and a dye. ### Claim 20 (depends on 3) The composition of claim 3, further comprising one or more components selected from the group consisting of a conditioner, a pigment, and a dye. ### Claim 21 (depends on 4) The composition of claim 4, further comprising one or more components selected from the group consisting of a conditioner, a pigment, and a dye. ### Claim 22 (depends on 6) The composition of claim 6, further comprising one or more components selected from the group consisting of a conditioner, a pigment, and a dye. ### Claim 23 (depends on 1) The composition of claim 1, wherein the UFP particles are substantially spherical.