# US 10,500,554 B2 · System and method for receiving a single-use vessel > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,500,554 B2 - Document ID: US10500554B2 - Status: Granted - Kind: B2 - Application number: 15/904,969 - Filed: 2018-02-26 - Published: 2018-07-05 - Granted: 2019-12-10 - Earliest claimed: 2016-01-29 - Assignees: Sartorius Stedim Biotech GmbH - Applicants: Sartorius Stedim Biotech GmbH - Inventors: Lars Boettcher; Jonathan Cutting; Sharon D. West; Martin Oschwald - Web page: https://patentgrep.com/patent/US10500554B2 ## CPC - B01F 35/2207: {Use of data, i.e. barcodes, 3D codes or similar type of tagging information, as instruction or identification codes for controlling the computer programs, e.g. for manipulation, handling, production or compounding in mixing plants (B01F33/848 takes precedence)} - B01F 27/808: with stirrers driven from the bottom of the receptacle - B01F 27/811: {with the inflow from one side only, e.g. stirrers placed on the bottom of the receptacle, or used as a bottom discharge pump} - B01F 27/88: with a separate receptacle-stirrer unit that is adapted to be coupled to a drive mechanism - B01F 27/91: with propellers - B01F 33/5023: {the vehicle being a trailer which is hand moved or coupled to self-propelling vehicles} - B01F 33/5024: {the vehicle being moved by human force} - B01F 35/513: Flexible receptacles, e.g. bags supported by rigid containers - B01F 35/514: {the mixing receptacle or conduit being transparent or comprising transparent parts} - B65D 25/205: {Means for the attachment of labels, cards, coupons or the like; (cards or coupons for the other types of rigid or semi-rigid containers B65D25/36 takes precedence)} - C12M 23/14: {Bags} - C12M 23/26: {flexible (flexible containers for laboratory use B01L3/505)} - C12M 23/28: {disposable or single use} - C12M 27/02: {Stirrer or mobile mixing elements} - G06K 7/10366: {the interrogation device being adapted for miscellaneous applications} - B01F 35/3211: {independent from the receptacle} - B01F 35/3213: {at the lower side of the axis, e.g. driving the stirrer from the bottom of a receptacle} - B01F 35/333: {the rotation sense being changeable, e.g. to mix or aerate, to move a fluid forward or backward or to suck or blow} - B01F 2101/44: Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation - B01F: MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING (mixing paints B44D3/06) - B65D: CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES - C12M: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; {APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS} - G06K: GRAPHICAL DATA READING (image or video recognition or understanding G06V); PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS ## Abstract A system for receiving a single-use vessel containing a mixing device has a support structure adapted to receive the single-use vessel and a drive-unit adapted to power, to control, or to power and control a mixing of contents of the single-use vessel when the single-use vessel is arranged in the support structure. The support structure and the drive-unit are provided as separate components that may be arranged both in an operating position, where the drive-unit is connectable to the mixing device of the single-use bag in the support structure, and in a separated position, where the drive-unit is separated from the support structure. The drive-unit comprises a tag reader that, in the operating position, is arranged to read a vessel tag of the single-use vessel arranged in the support structure. ## Claims ### Claim 1 A single-use bioreactor vessel for mixing media therein, the single use bioreactor vessel comprising: a flexible bag having at least one flexible wall defining an enclosure for the media to be mixed; at least one sensor mounted in the flexible wall; and a vessel tag at a position facing substantially outwards, the vessel tag carrying readable information identifying the flexible bag and identifying the at least one sensor, wherein the single-use bioreactor vessel is configured to be received by a support structure of a system such that the vessel tag is arranged to be read by a tag reader of the system so that the tag reader reads the readable information identifying the flexible bag and identifying the at least one sensor. ### Claim 2 (depends on 1) The single-use bioreactor vessel of claim 1, wherein the flexible bag is made of a flexible multilayer film. ### Claim 3 (depends on 1) The single-use bioreactor vessel of claim 1, further comprising a mixing device at a bottom side of the flexible bag, the mixing device being configured to be connected to an external motor for powering the mixing device. ### Claim 4 (depends on 3) The single-use bioreactor vessel of claim 3, wherein the vessel tag is arranged at a predetermined position relative to the mixing device. ### Claim 5 (depends on 1) The single-use bioreactor vessel of claim 1, wherein the readable information carried by the vessel tag and identifying the flexible bag comprises at least one of: a product code, a product type, a serial number, a lot number, a flexible bag volume, manufacturing date, irradiation date, expiration dates, and manufacturer test results. ### Claim 6 (depends on 3) The single-use bioreactor vessel of claim 3, wherein the mixing device comprises an impeller arranged within the flexible bag, the readable information carried by the vessel tag and identifying the flexible bag comprises information identifying the mixing impeller. ### Claim 7 (depends on 1) The single-use bioreactor vessel of claim 1, wherein the vessel tag is a 2D bar code. ### Claim 8 (depends on 1) The single-use bioreactor vessel of claim 1, wherein the vessel tag is an RFID tag. ### Claim 9 (depends on 1) The single-use bioreactor vessel of claim 1, wherein the flexible bag further comprises a powder port and wherein the readable information carried by the vessel tag and identifying the flexible bag comprises information identifying the powder port. ### Claim 10 (depends on 1) The single-use bioreactor vessel of claim 1, wherein the flexible bag further comprises at least one liquid port and wherein the readable information carried by the vessel tag and identifying the flexible bag comprises information identifying the at least one liquid port. ### Claim 11 (depends on 1) The single-use bioreactor vessel of claim 1, further comprising: a mixing device at a bottom side of the flexible bag, the mixing device being accessible from an exterior of the flexible bag and configured to be connected to an external motor for powering the mixing device; wherein: the at least one sensor is mounted at a specified position spaced from the mixing device and positioned to be connected to an external connection when the mixing device is connected to the external motor, and the vessel tag aligns with the tag reader when the port or the sensor is connected to an external connection and when the mixing device is connected to the external motor. ### Claim 12 (depends on 11) The single-use bioreactor vessel of claim 11, wherein the readable information carried by the vessel tag and identifying the flexible bag comprises readable information identifying impeller characteristics. ### Claim 13 (depends on 1) The single-use bioreactor vessel of claim 1, wherein the vessel tag further carries readable information pertaining to sensor calibration information of the at least one sensor. ### Claim 14 (depends on 1) The single-use bioreactor vessel of claim 1, wherein the vessel tag further carries readable information pertaining to manufacturing date. ### Claim 15 (depends on 5) The single-use bioreactor vessel of claim 5, wherein the readable information carried by the vessel tag and identifying the at least one sensor comprises: information about sensor features of the at least one sensor, and sensor calibration information of the at least one sensor. ### Claim 16 (depends on 1) The single-use bioreactor vessel of claim 1, further comprising a tag reader disposed and configured for reading the readable information identifying the flexible bag and identifying the at least one sensor.