# US 10,500,411 B2 · Cancer cell growth inhibition and killing device using blue light LED

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- Number: US 10,500,411 B2
- Document ID: US10500411B2
- Status: Granted
- Kind: B2
- Application number: 15/324,036
- Filed: 2015-07-09
- Published: 2017-06-08
- Granted: 2019-12-10
- Earliest claimed: 2014-07-09
- Assignees: Industrial Cooperation Foundation Chonbuk National University
- Applicants: Industrial Cooperation Foundation Chonbuk National University
- Inventors: Hwan-Jeong Jeong
- Web page: https://patentgrep.com/patent/US10500411B2

## CPC

- A61N 5/0613: {Apparatus adapted for a specific treatment}
- A61N 5/0616: {Skin treatment other than tanning}
- A61N 2005/0638: {with a specially adapted support surface}
- A61N 2005/064: {in a vertical position}
- A61N 2005/0652: {Arrays of diodes}
- A61N 2005/0663: {Coloured light}
- A61N 2005/0666: {for redirecting light to the treatment area}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

Provided is a cancer cell growth inhibition and killing device using a blue light LED. The present invention comprises: a bed part which has a top plate on which the body is laid to stand by; a main body part provided with a treatment space, which has a predetermined size and on which the bed part is disposed, and having a chamber which is divided by the treatment space and a transparent plate formed of a light-transmitting material to thus form a treatment light generation space; and a treatment light generation unit which generates a treatment light having a wavelength band of a predetermined size when power is applied so that the treatment light can penetrate the subcutaneous tissue of the body and thereby stimulate and kill cancer cells moving along blood vessels, and which is provided in the chamber so as to irradiate the treatment space with the treatment light after the treatment light has penetrated though the transparent plate.

## Claims

### Claim 1

A cancer cell growth inhibition and killing device using a blue light LED,
the device comprising:
a bed part which has a top plate configured to support a body of a patient, wherein the bed part includes a vertical table having a predetermined length of which an upper end is rotatably supported through a hinge pin on the lower surface of the top plate and front and rear cylinder members of which load front ends are connected to front and rear lower surfaces of the top plate through the pin member and are vertically operated to obliquely shift a horizontal state of the top plate based on the hinge pin, respectively;
a main body part provided with a treatment space, which has a predetermined size and on which the bed part is disposed, and having a chamber which is divided by the treatment space and a transparent plate formed of a light-transmitting material to thus form a treatment light generation space; and
a treatment light generation unit which is configured to generate a blue treatment light consisting of a wavelength band of 450 nm to 470 nm when power is applied so that the blue treatment light can penetrate the subcutaneous tissue of the body and thereby stimulate and kill cancer cells moving along blood vessels, and which is provided in the chamber so as to irradiate the treatment space with the blue treatment light after the blue treatment light has penetrated though the transparent plate,
wherein the patient's body is supported by the bed part, the patient having previously been diagnosed as having cancer, and
wherein the blue treatment light is capable of (1) increasing expression of cleaved caspase-3 cleaved in cancel cells of the patient and (2) increasing production of reactive oxygen species (ROS) and phosphorylation of p53 in cancer cells of the patient.

### Claim 2 (depends on 1)

The cancer cell growth inhibition and killing device of claim 1, wherein the treatment light generation unit includes LEDs that generate the blue treatment light consisting of a wavelength band of 450 to 470 nm when the power is applied, lenses that guide light so that the blue treatment light generated in the LED is convergence-irradiated to the body, and heat dissipation members that discharge heat generated when the light of the LED is emitted to the outside so that a central wavelength of the blue treatment light is not changed.

### Claim 3 (depends on 1)

The cancer cell growth inhibition and killing device of claim 1, wherein the main body part includes at least one ventilation fan at the outside of the chamber corresponding to the treatment light generation space to ventilate indoor air in the treatment light generation space to the outside.

### Claim 4 (depends on 1)

The cancer cell growth inhibition and killing device of claim 1, wherein the main body part includes a reflective sheet that reflects the treatment light to the inner surface to enhance a light irradiation rate for the living body.

### Claim 5 (depends on 1)

The cancer cell growth inhibition and killing device of claim 1, wherein the main body part includes an upper main body part having the upper treatment light generation space based on the bed part, a lower main body part having the lower treatment light generation space, and a hinge member pivoting the upper main body part with respect to the lower main body part to open and close the treatment space.

### Claim 6 (depends on 1)

The cancer cell growth inhibition and killing device of claim 1, wherein the vertical table includes an internal pipe having a predetermined length of which an upper end is connected to the top plate through the hinge pin and an external pipe having a predetermined length to which a lower end of the internal pipe is inserted to be vertically guided.