# US 10,500,182 B2 · Compositions of ketogenic sources, micronutrients and phytochemicals for prophylaxis and mitigation of migraine headache

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- Number: US 10,500,182 B2
- Document ID: US10500182B2
- Status: Granted
- Kind: B2
- Application number: 16/501,249
- Filed: 2019-03-13
- Published: 2019-07-11
- Granted: 2019-12-10
- Earliest claimed: 2018-01-10
- Applicants: Robert Firger; Gerald Haase
- Inventors: Robert Firger; Gerald Haase
- Web page: https://patentgrep.com/patent/US10500182B2

## CPC

- A61K 31/23: of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K 31/12: Ketones
- A61K 31/122: having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K 31/22: of acyclic acids, e.g. pravastatin
- A61K 31/341: not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
- A61K 31/355: Tocopherols, e.g. vitamin E
- A61K 31/4045: Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
- A61K 31/4415: Pyridoxine, i.e. Vitamin B6 (pyridoxal phosphate A61K31/675)
- A61K 31/522: having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
- A61K 31/525: Isoalloxazines, e.g. riboflavins, vitamin B2
- A61K 31/7084: Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
- A61K 33/06: Aluminium, calcium or magnesium; Compounds thereof {, e.g. clay}
- A61K 36/28: Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K 36/35: Caprifoliaceae (Honeysuckle family)
- A61K 36/53: Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K 36/534: Mentha (mint)
- A61K 36/889: Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
- A61K 36/9068: Zingiber, e.g. garden ginger
- A61P 25/06: Antimigraine agents
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

A formulation comprising at least one ketogenic source, at least one vitamin, at least one mineral, at least one antioxidant, optionally at least one phytonutrient, and optionally at least one other nutrient, and mixtures and combinations thereof intended for the prevention and mitigation of migraine headache.

## Claims

### Claim 1

A formulation comprising at least one ketogenic source from about 1 to about 60 g, at least one vitamin from about 1 to about 2,000 mg, at least one mineral from about 50 to about 500 mg, at least one antioxidant from about 5 to about 2,000 mg, at least one phytonutrient from about 5 to about 5,000 mg, and at least one nutrient from about 0.1 to about 250 mg, said at least one ketogenic source is selected from the group consisting of medium chain triglycerides, coconut capsule, palm capsule, medium chain triglyceride oils, caprylic acid, capric acid, medium chain triglyceride powder, coconut oil extracts, caproic acid, lauric acid, ketone salts, ketone esters, and mixtures and combinations thereof said at least one vitamin is selected from the group consisting of Vitamin B2, Vitamin B3, nicotinamide riboside, nicotinamide adenine dinucleotide or vitamin B6, said at least one mineral is selected from the group consisting of magnesium citrate, magnesium lactate, magnesium gluconate, magnesium oxide, magnesium carbonate, magnesium hydroxide, magnesium chloride, magnesium sulphate, tribasic phosphate, and mixtures and combinations thereof, said at least one antioxidant is selected from the group consisting of Vitamin C, ascorbate salts, citrus, rose, berry source, Vitamin E, vegetable products, wheat germ products, natural tocopherol, d-alpha tocopheryl succinate, d-alpha tocopheryl acetate, Coenzyme Q10, ubiquinone, organ meat, natural ingredient sources, Agrobacterium tumefaciens, Paracoccus denitrificans, Pseudomonas aeruginosa, and mixtures or combinations thereof, said phytonutrients are selected from the group consisting of basil, butterbur, feverfew, ginger, peppermint, Valerian, and mixtures and combinations thereof, and said nutrients are selected from the group consisting of melatonin, caffeine, peppermint essential oil, and mixtures and combinations thereof.

### Claim 2 (depends on 1)

The formulation of claim 1 wherein said formulation is utilized to treat, prevent, and relieve the symptoms of a migraine headache.