# US 10,500,155 B2 · Lozenge dosage form having a disintegrative tablet portion and a candy glass shell portion

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 10,500,155 B2
- Document ID: US10500155B2
- Status: Granted
- Kind: B2
- Application number: 15/879,740
- Filed: 2018-01-25
- Published: 2018-11-22
- Granted: 2019-12-10
- Earliest claimed: 2017-05-22
- Assignees: Johnson & Johnson Consumer Inc.
- Applicants: Johnson & Johnson Consumer Inc.
- Inventors: Gerard P. McNally; Gregory Koll; Oliver Anderson
- Web page: https://patentgrep.com/patent/US10500155B2

## CPC

- A61K 9/0056: {Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals}
- A23G 3/38: Sucrose-free products
- A23G 3/54: Composite products, e.g. layered, coated, filled
- A61K 9/209: {containing drug in at least two layers or in the core and in at least one outer layer}
- A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs
- A23V 2250/5118: Starch
- A23V 2250/6422: Xylitol
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23G: COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION

## Abstract

The present invention relates to a lozenge dosage form having a disintegrative tablet portion and a candy glass shell portion.

## Claims

### Claim 1

A lozenge dosage form comprising:
a disintegrative tablet portion; and
a candy glass shell portion;
wherein the disintegrative tablet portion comprises at least one pharmaceutically active ingredient;
wherein the disintegrative tablet portion has a form of a plug as depicted in FIG. 3;
wherein the plug is added to the candy glass shell portion after the candy glass shell portion is formed;
wherein pressure and/or heat is added to the plug to fill in a predefined space within the candy glass shell portion;
wherein the candy glass shell portion has a form of a spherical cap as depicted in FIG. 1; and
wherein when combined the disintegrative tablet portion and the candy glass shell portion have a form as depicted in FIG. 2.

### Claim 2 (depends on 1)

The lozenge dosage form of claim 1, wherein the candy glass shell portion comprises at least one pharmaceutically active ingredient.

### Claim 3 (depends on 1)

The lozenge dosage form of claim 1, wherein the disintegrative tablet portion comprises at least two excipients selected from the group consisting of a poloxamer, polyethylene glycol, a sugar, a starch and a starch hydrosylate.

### Claim 4 (depends on 1)

The lozenge dosage form of claim 1, wherein the disintegrative tablet portion comprises multiple layers.

### Claim 5 (depends on 4)

The lozenge dosage form of claim 4, wherein the disintegrative tablet portion comprises two layers, wherein a first layer comprises a first pharmaceutically active ingredient, and wherein a second layer comprises a second pharmaceutically active ingredient.

### Claim 6 (depends on 5)

The lozenge dosage form of claim 5, wherein the first layer and the second layer are exposed on a surface of the dosage form.

### Claim 7 (depends on 1)

A method of treating an ailment comprising orally administering the lozenge dosage form of claim 1.