# US 10,500,152 B2 · Skin lightening compositions

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- Number: US 10,500,152 B2
- Document ID: US10500152B2
- Status: Granted
- Kind: B2
- Application number: 15/816,026
- Filed: 2017-11-17
- Published: 2018-03-15
- Granted: 2019-12-10
- Earliest claimed: 2014-03-10
- Assignees: Mary Kay Inc.
- Applicants: Mary Kay Inc.
- Inventors: David Gan; Tiffany Carle; Michelle Hines; Patricia Jacoby; Wanli Zhao; Julia Collier; Edward Chadwick; Mauricio Castro; Barbara Durkee; Daniel Ramirez
- Web page: https://patentgrep.com/patent/US10500152B2

## CPC

- A61K 8/347: {Phenols}
- A61K 8/25: Silicon; Compounds thereof
- A61K 8/29: Titanium; Compounds thereof
- A61K 8/31: Hydrocarbons
- A61K 8/345: {containing more than one hydroxy group}
- A61K 8/35: Ketones, e.g. benzophenone
- A61K 8/36: Carboxylic acids; Salts or anhydrides thereof
- A61K 8/368: with carboxyl groups directly bound to carbon atoms of aromatic rings
- A61K 8/37: Esters of carboxylic acids
- A61K 8/41: Amines
- A61K 8/42: Amides
- A61K 8/4926: {having six membered rings}
- A61K 8/494: {with more than one nitrogen as the only hetero atom}
- A61K 8/4973: {with oxygen as the only hetero atom}
- A61K 8/585: {Organosilicon compounds}
- A61K 8/675: {Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde (tocopheryl nicotinate A61K8/678)}
- A61K 8/73: Polysaccharides
- A61K 8/738: {Cyclodextrins}
- A61K 8/8141: {Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers}
- A61K 8/8158: {Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers}
- A61K 8/92: Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K 8/9711: Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
- A61K 8/9767: Pinaceae [Pine family], e.g. pine or cedar
- A61K 8/9789: Magnoliopsida [dicotyledons]
- A61Q 19/02: for chemically bleaching or whitening the skin
- A61K 2800/59: Mixtures
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

Disclosed are compositions and methods for their use that include a combination of Leontopodium alpinum extract, Halidrys siliquosa extract, vegetable amino acids, niacinamide, hexylresorcinol, Pinus pinaster extract, Betula alba extract, Albizia julibrissin bark extract, hydrolyzed Candida saitoana extract, Lentinus edodes mycelium extract, and/or Opuntia tuna fruit extract.

## Claims

### Claim 1

A method for whitening or lightening skin, the method comprising topically applying to skin in need thereof a composition comprising an effective amount of a liquid aqueous navy bean extract having amino acids, wherein the composition whitens or lightens the skin.

### Claim 2 (depends on 1)

The method of claim 1, wherein the composition is applied to hyperpigmented skin.

### Claim 3 (depends on 1)

The method of claim 1, wherein the composition is applied to a freckle or dark spot on skin.

### Claim 4 (depends on 1)

The method of claim 1, wherein the composition is applied to skin having an uneven skin tone from excess melanin pigmentation.

### Claim 5 (depends on 1)

The method of claim 1, wherein the composition inhibits melanogenesis in the skin.

### Claim 6 (depends on 1)

The method of claim 1, wherein the composition comprises 0.001 to 5.0 wt. % of the aqueous navy bean extract.

### Claim 7 (depends on 1)

The method of claim 1, wherein the composition further includes niacinamide.

### Claim 8 (depends on 1)

The method of claim 1, wherein the composition further includes an effective amount of hexylresorcinol to inhibit glycation in the skin.

### Claim 9 (depends on 1)

The method of claim 1, wherein the composition is an emulsion.

### Claim 10 (depends on 9)

The method of claim 9, wherein the emulsion is an oil-in-water emulsion.

### Claim 11 (depends on 1)

The method of claim 1, wherein the composition is an aqueous solution.

### Claim 12 (depends on 1)

The method of claim 1, wherein the composition is a cream or lotion.

### Claim 13 (depends on 1)

The method of claim 1, wherein the composition further comprises a chelating agent, a moisturizing agent, a preservative, a thickening agent, and an emulsifier.