# US 10,500,147 B2 · Toothpaste with alginate based rheology modifier > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,500,147 B2 - Document ID: US10500147B2 - Status: Granted - Kind: B2 - Application number: 15/113,933 - Filed: 2014-01-24 - Published: 2016-12-01 - Granted: 2019-12-10 - Earliest claimed: 2014-01-24 - Assignees: Colgate-Palmolive Company - Applicants: Colgate-Palmolive Company - Inventors: Xiaojing Lv; Manying Shi; Zhuoxing Zhang - Web page: https://patentgrep.com/patent/US10500147B2 ## CPC - A61K 8/60: Sugars; Derivatives thereof - A61K 8/19: containing inorganic ingredients - A61K 8/345: {containing more than one hydroxy group} - A61K 8/463: {containing sulfuric acid derivatives, e.g. sodium lauryl sulfate} - A61K 8/731: {Cellulose; Quaternized cellulose derivatives} - A61K 8/733: {Alginic acid; Salts thereof} - A61Q 11/00: Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses - A61Q 17/005: {Antimicrobial preparations} - A61K 2800/28: Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants - A61K 2800/34: Free of silicones - A61K 2800/48: Thickener, Thickening system - A61K 2800/59: Mixtures - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS ## Abstract The present invention provides oral care compositions, and in particular toothpaste compositions comprising a calcium salt abrasive and a novel alginate-based binder and rheology modifier, together with methods of use and manufacture thereof. ## Claims ### Claim 1 A toothpaste comprising a binder system and a calcium salt abrasive, wherein the binder system comprises sodium calcium alginate having a sodium:calcium ratio of from 7:1 to 4:1, wherein the sodium calcium alginate is present in the toothpaste in an amount of from 0.09% to 0.1% of the toothpaste by weight, and the toothpaste further comprises carboxymethylcellulose in an amount of from 0.5% to 1.5% of the toothpaste by weight. ### Claim 2 (depends on 1) The toothpaste of claim 1, wherein the abrasive comprises calcium carbonate in an amount of from 25% to 60% of the toothpaste by weight. ### Claim 3 (depends on 1) The toothpaste of claim 1 that is free of magnesium aluminum silicate. ### Claim 4 (depends on 1) The toothpaste of claim 1 further comprising a humectant that comprises one or more polyols in an amount of from 16% to 26% of the toothpaste by weight. ### Claim 5 (depends on 1) The toothpaste of claim 1, further comprising one or more detergents or surfactants in an amount of from 1% to 3% of the toothpaste by weight. ### Claim 6 (depends on 1) The toothpaste of claim 1, further comprising a fluoride source in an amount sufficient to provide about 1100 ppm of fluoride ion by weight. ### Claim 7 (depends on 1) The toothpaste of claim 1, wherein: the binder comprises sodium calcium alginate having a sodium:calcium ratio of from 7:1 to 4:1; the sodium calcium alginate binder is present in the toothpaste in an amount of about 0.1%, of the toothpaste by weight; the abrasive comprises natural calcium carbonate, in an amount of from 40% to 45%, of the toothpaste by weight; and the toothpaste further comprises carboxymethylcellulose in an amount of from 0.5% to 1.5% of the toothpaste by weight. ### Claim 8 (depends on 7) The toothpaste of claim 7, further comprising: from 16% to 26% sorbitol; from 1% to 3% sodium lauryl sulfate, and from 0.5% to 2% of a fluoride source, of the toothpaste by weight. ### Claim 9 (depends on 1) The toothpaste of claim 1, further comprising thickener silica in an amount of from 1% to 3% of the toothpaste by weight. ### Claim 10 (depends on 1) The toothpaste of claim 1, further comprising one or more adjuvants selected from sweetening agents, flavoring agents and coloring agents. ### Claim 11 (depends on 1) The toothpaste of claim 1, comprising a flavoring agent in an amount of from 0.5% to 2.0% of the toothpaste by weight. ### Claim 12 (depends on 1) The toothpaste of claim 1 comprising: a binder system comprising sodium calcium alginate having a sodium:calcium ratio of about 84:16, and which is present in the toothpaste in an amount of about 0.1%, of the toothpaste by weight; natural calcium carbonate abrasive, in an amount of about 42%, of the toothpaste by weight; carboxymethylcellulose in an amount of about 1%, of the toothpaste by weight; sorbitol in an amount of about 21% of the toothpaste by weight; sodium lauryl sulfate in an amount of about 2%, of the toothpaste by weight; a fluoride source, in an amount to provide about 1100 ppm fluoride ion by weight; and thickener silica in an amount of about 2% of the toothpaste by weight. ### Claim 13 (depends on 1) The toothpaste of claim 1, wherein the toothpaste is a striped toothpaste. ### Claim 14 (depends on 1) A method for reducing bacterial growth, cleaning the teeth, removing dental plaque, reducing dental erosion, treating dental hypersensitivity, treating gingivitis, and/or reducing tooth decay in an oral cavity, comprising contacting the oral cavity with a toothpaste of claim 1. ### Claim 15 (depends on 4) The toothpaste of claim 4 wherein the one or more polyols comprise sorbitol. ### Claim 16 A toothpaste comprising a binder system and an calcium salt abrasive, wherein the binder system comprises sodium calcium alginate having a sodium:calcium ratio of from 7:1 to 4:1, wherein the sodium calcium alginate is present in the toothpaste in an amount of about 0.1% of the toothpaste by weight, and the toothpaste further comprises carboxymethylcellulose in an amount of from 0.5% to 1.5% of the toothpaste by weight.