# US 10,500,077 B2 · Support for treating vascular bifurcations > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,500,077 B2 - Document ID: US10500077B2 - Status: Granted - Kind: B2 - Application number: 14/396,688 - Filed: 2013-03-11 - Published: 2015-04-30 - Granted: 2019-12-10 - Earliest claimed: 2012-04-26 - Assignees: Poseidon Medical Inc. - Applicants: Tryton Medical, Inc. - Inventors: H. Richard Davis; Aaron Kaplan - Web page: https://patentgrep.com/patent/US10500077B2 ## CPC - A61F 2/91: made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes - A61F 2/88: the wire-like elements formed as helical or spiral coils - A61F 2/856: Single tubular stent with a side portal passage - A61F 2/954: for placing stents or stent-grafts in a bifurcation - A61F 2/958: Inflatable balloons for placing stents or stent-grafts - A61F 2002/061: {provided with means for allowing access to secondary lumens} - A61F 2002/821: {Ostial stents} - A61F 2002/91508: {the meander having a difference in amplitude along the band} - A61F 2002/91525: {within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude} - A61F 2002/91541: {Adjacent bands are arranged out of phase} - A61F 2002/91558: {connected peak to peak} - A61F 2002/91575: {connected peak to trough} - A61F 2250/003: differing in adsorbability or resorbability, i.e. in adsorption or resorption time - A61F 2250/0031: made from both resorbable and non-resorbable prosthetic parts, e.g. adjacent parts - A61F 2250/0035: differing in release or diffusion time - A61F 2250/0067: Means for introducing or releasing pharmaceutical products into the body - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) ## Abstract A prosthesis is disclosed for placement across an ostium opening from a main body lumen to a branch body lumen. The prosthesis has a radially expansible support and a bifurcation traversing portion. The radially expansible support is configured to be deployed in at least a portion of the branch body lumen. The bifurcation traversing portion has a biostable portion having a first end and a second end. The first end is located adjacent to the radially expansible support. The bifurcation traversing portion also has a biodegradable portion having a first end coupled with the second end of the biostable portion. The biodegradable portion has a second end disposed at an end of the prosthesis opposite the radially expansible support. When deployed, the bifurcation traversing portion extends from the radially expansible support across a bifurcation and into a main body lumen such that the carina is supported thereby. ## Claims ### Claim 1 A prosthesis for placement at an ostium opening from a main body lumen to a branch body lumen, the prosthesis comprising: a radially expansible support configured to be deployed in at least a portion of the branch body lumen; and a bifurcation traversing portion having a biostable portion having a first end and a second end, the first end being located adjacent to the radially expansible support and a biodegradable portion having a first end coupled with the second end of the biostable portion and a second end disposed at an end of the prosthesis opposite the radially expansible support, the bifurcation traversing portion comprising an interlock device configured to mechanically couple the biodegradable and biostable portions, the interlock device comprising a biodegradable section adjacent the biodegradable portion and a biostable section adjacent the biostable portion, the interlock device having a protrusion and a jaw member, the jaw member comprising first and second spaced apart portions configured to be moved toward each other to engage with the protrusion at least in the unexpanded state; wherein when deployed, the bifurcation traversing portion extends from the radially expansible support across a bifurcation and into a main body lumen such that the ostium opening is supported thereby. ### Claim 2 (depends on 1) The prosthesis of claim 1, wherein the jaw member is mechanically coupled with the protrusion. ### Claim 3 (depends on 1) The prosthesis of claim 1, wherein the bifurcation traversing portion comprises a plurality of longitudinal members, each longitudinal member comprising an axially extending part of the biostable portion, an axially extending part of the biodegradable portion, the jaw member disposed on the axially extending part of the biostable portion and the protrusion disposed on the axially extending part of the biodegradable portion, the jaw member and protrusion being configured to mechanically couple the axially extending parts of the biostable and biodegradable portions. ### Claim 4 (depends on 1) The prosthesis of claim 1, wherein the biostable portion comprises a transition zone disposed adjacent to the support and being adapted to expand to cover the ostium and wherein the bifurcation traversing portion comprises a plurality of longitudinal members extending from the second end of the biodegradable portion toward the first end of the biostable portion. ### Claim 5 (depends on 4) The prosthesis of claim 4, further comprising a circumferential member extending between at least two of the longitudinal members to stabilize or position the longitudinal members within the main body lumen during a deployment procedure. ### Claim 6 (depends on 5) The prosthesis of claim 5, wherein at least one of the longitudinal members comprises a frond. ### Claim 7 (depends on 6) The prosthesis of claim 6 wherein the frond comprises a transition portion having a first end coupled with the support and a plurality of second ends spaced apart from each other and from the support. ### Claim 8 (depends on 1) The prosthesis of claim 1, wherein a portion of the bifurcation traversing portion comprises an axially oriented pattern of undulating filaments and wherein the first and second spaced apart portions of the jaw member of the interlock device comprise two filaments at a junction of the biostable and biodegradable portions. ### Claim 9 (depends on 1) The prosthesis of claim 1, wherein the support has a first wall comprising a first wall pattern, and the bifurcation traversing portion has a second wall comprising a second wall pattern different from the first wall pattern. ### Claim 10 (depends on 9) The prosthesis of claim 9, wherein the second wall has a circumferential surface area that is lower toward a proximal end thereof than adjacent to the radially expansible support. ### Claim 11 (depends on 1) The prosthesis of claim 1, wherein at least one of the biostable and the biodegradable portions comprises a serpentine or sinusoidal member. ### Claim 12 (depends on 11) The prosthesis of claim 11, wherein the biodegradable portion comprises a dual serpentine member. ### Claim 13 (depends on 1) The prosthesis of claim 1, wherein the first and second spaced apart portions include a narrow opening and a wider zone, and wherein the protrusion comprises a narrow neck and wider head such that the protrusion is configured to be inserted into the jaw member. ### Claim 14 (depends on 1) The prosthesis of claim 1, wherein the bifurcation traversing portion comprises a plurality of elongate members each comprising a first zone having two side-by-side filaments and a second zone comprising a single filament, and wherein a junction of the biostable and biodegradable portions is disposed in the first zone. ### Claim 15 (depends on 1) The prosthesis of claim 1, wherein the bifurcation traversing portion comprises a plurality of longitudinal members, each longitudinal member comprising an axially extending part of the biostable portion, an axially extending part of the biodegradable portion, the interlock device configured to mechanically couple the axially extending parts of the biostable and biodegradable portions. ### Claim 16 (depends on 15) The prosthesis of claim 15, wherein the axially extending parts of the biostable and biodegradable portions each comprises one or more undulating filaments. ### Claim 17 (depends on 16) The prosthesis of claim 16, wherein the one or more undulating filaments comprise two parallel undulating filaments. ### Claim 18 (depends on 1) The prosthesis of claim 1, wherein the biodegradable portion comprises a plurality of longitudinal members each comprising a first zone having two side-by-side axially oriented undulating filaments and a second zone comprising a single axially oriented undulating filament, and wherein the biodegradable portion further comprises a circumferential member. ### Claim 19 A prosthesis for placement at an ostium opening from a main body lumen to a branch body lumen, the prosthesis comprising: a radially expansible support configured to be deployed in at least a portion of the branch body lumen; and a bifurcation traversing portion having a biostable portion having a first end and a second end, the first end being located adjacent to the radially expansible support and a biodegradable portion having a first end coupled with the second end of the biostable portion and a second end disposed at an end of the prosthesis opposite the radially expansible support, the bifurcation traversing portion comprising an interlock device located between the biodegradable and biostable portions configured to mechanically couple the biodegradable and biostable portions, the interlock device having a protrusion and a jaw member, the jaw member comprising first and second spaced apart portions configured to be moved toward each other to engage with the protrusion at least in the unexpanded state; wherein when deployed, the bifurcation traversing portion extends from the radially expansible support across a bifurcation and into a main body lumen such that the ostium opening is supported thereby. ### Claim 20 (depends on 19) The prosthesis of claim 19, wherein the interlock device is located only between the biodegradable and biostable portions. ### Claim 21 (depends on 19) The prosthesis of claim 19, wherein the bifurcation traversing portion comprises a plurality of longitudinal members, each longitudinal member comprising an axially extending part of the biostable portion, an axially extending part of the biodegradable portion, the interlock device configured to mechanically couple the axially extending parts of the biostable and biodegradable portions. ### Claim 22 (depends on 19) The prosthesis of claim 19, wherein the biostable portion comprises a transition zone disposed adjacent to the support and being adapted to expand to cover the ostium and wherein the bifurcation traversing portion comprises a plurality of longitudinal members extending from the second end of the biodegradable portion toward the first end of the biostable portion. ### Claim 23 (depends on 22) The prosthesis of claim 22, further comprising a circumferential member extending between at least two of the longitudinal members to stabilize or position the longitudinal members within the main body lumen during a deployment procedure. ### Claim 24 (depends on 23) The prosthesis of claim 23, wherein at least one of the longitudinal members comprises a frond. ### Claim 25 (depends on 19) The prosthesis of claim 19, wherein the first and second spaced apart portions include a narrow opening and a wider zone, and wherein the protrusion comprises a narrow neck and wider head such that the protrusion is configured to be inserted into the jaw member. ### Claim 26 A prosthesis for placement at an ostium opening from a main body lumen to a branch body lumen, the prosthesis comprising: a radially expansible support configured to be deployed in at least a portion of the branch body lumen, the support comprising a first plurality of connectors of a first configuration; and a bifurcation traversing portion having a biostable portion having a first end and a second end, the first end being located adjacent to the radially expansible support and a biodegradable portion having a first end coupled with the second end of the biostable portion and a second end disposed at an end of the prosthesis opposite the radially expansible support, the bifurcation traversing portion comprising a second plurality of connectors of a second configuration different from the first configuration, the second plurality of connectors comprising an interlock device located between the biodegradable and biostable portions, the interlock device having a protrusion and a jaw member, the jaw member comprising first and second spaced apart portions configured to be moved toward each other to engage with the protrusion at least in the unexpanded state; wherein when deployed, the bifurcation traversing portion extends from the radially expansible support across a bifurcation and into a main body lumen such that the ostium opening is supported thereby. ### Claim 27 (depends on 26) The prosthesis of claim 26, wherein the interlock device is located only between the biodegradable and biostable portions. ### Claim 28 (depends on 26) The prosthesis of claim 26, wherein the first plurality of connectors are disposed at a plurality of locations within the support and configured to couple adjacent rings of the support. ### Claim 29 (depends on 26) The prosthesis of claim 26, wherein the first plurality of connectors are disposed at one or more apexes. ### Claim 30 (depends on 26) The prosthesis of claim 26, wherein the first plurality of connectors comprise axially extending struts. ### Claim 31 (depends on 26) The prosthesis of claim 26, wherein the bifurcation traversing portion comprises a plurality of longitudinal members, each longitudinal member comprising an axially extending part of the biostable portion, an axially extending part of the biodegradable portion, the interlock device configured to mechanically couple the axially extending parts of the biostable and biodegradable portions. ### Claim 32 (depends on 26) The prosthesis of claim 26, wherein the biostable portion comprises a transition zone disposed adjacent to the support and being adapted to expand to cover the ostium and wherein the bifurcation traversing portion comprises a plurality of longitudinal members extending from the second end of the biodegradable portion toward the first end of the biostable portion. ### Claim 33 (depends on 32) The prosthesis of claim 32, further comprising a circumferential member extending between at least two of the longitudinal members to stabilize or position the longitudinal members within the main body lumen during a deployment procedure. ### Claim 34 (depends on 33) The prosthesis of claim 33, wherein at least one of the longitudinal members comprises a frond. ### Claim 35 (depends on 26) The prosthesis of claim 26, wherein the first and second spaced apart portions include a narrow opening and a wider zone, and wherein the protrusion comprises a narrow neck and wider head such that the protrusion is configured to be inserted into the jaw member. ### Claim 36 A prosthesis for placement at an ostium opening from a main body lumen to a branch body lumen, the prosthesis comprising: a radially expansible support configured to be deployed in at least a portion of the branch body lumen; and a bifurcation traversing portion having a biostable portion having a first end and a second end, the first end being located adjacent to the radially expansible support and a biodegradable portion having a first end coupled with the second end of the biostable portion and a second end disposed at an end of the prosthesis opposite the radially expansible support, the bifurcation traversing portion comprising an interlock device having a protrusion and a jaw member, the jaw member comprising first and second spaced apart portions configured to be moved toward each other to engage with the protrusion at least in the unexpanded state; wherein when deployed, the bifurcation traversing portion extends from the radially expansible support across a bifurcation and into a main body lumen such that the ostium opening is supported thereby, wherein the biodegradable portion comprises a plurality of longitudinal members each comprising a first zone having two side-by-side axially oriented undulating filaments and a second zone comprising a single axially oriented undulating filament such that the filaments reduce in number from the first zone to the second zone, wherein the biodegradable portion further comprises a circumferential member, and wherein the biostable portion comprises a plurality of longitudinal members, each longitudinal member of the biostable and biodegradable portions comprising an axially extending part, the interlock device configured to mechanically couple the axially extending parts of the biostable and biodegradable portions. ### Claim 37 (depends on 36) The prosthesis of claim 36, wherein the biostable portion comprises a transition zone disposed adjacent to the support and being adapted to expand to cover the ostium. ### Claim 38 (depends on 37) The prosthesis of claim 37, further comprising a circumferential member extending between at least two of the longitudinal members of the biodegradable portion to stabilize or position the longitudinal members within the main body lumen during a deployment procedure. ### Claim 39 (depends on 38) The prosthesis of claim 38, wherein at least one of the longitudinal members comprises a frond. ### Claim 40 (depends on 36) The prosthesis of claim 36, wherein the first and second spaced apart portions include a narrow opening and a wider zone, and wherein the protrusion comprises a narrow neck and wider head such that the protrusion is configured to be inserted into the jaw member.