# US 10,499,939 B2 · Galvanically assisted attachment of medical devices to thrombus

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- Number: US 10,499,939 B2
- Document ID: US10499939B2
- Status: Granted
- Kind: B2
- Application number: 15/605,169
- Filed: 2017-05-25
- Published: 2017-09-14
- Granted: 2019-12-10
- Earliest claimed: 2013-11-13
- Assignees: Covidien LP
- Applicants: Covidien LP
- Inventors: James Davidson
- Web page: https://patentgrep.com/patent/US10499939B2

## CPC

- A61B 17/221: Gripping devices in the form of loops or baskets {for gripping calculi or similar types of obstructions (surgical snare instruments A61B17/32056)}
- A61F 2/0105: {Open ended, i.e. legs gathered only at one side}
- A61N 1/378: Electrical supply
- A61B 2017/00831: {Material properties}
- A61B 2017/00929: {isolating electrical current}
- A61B 2017/22001: {Angioplasty, e.g. PCTA}
- A61B 2017/22034: {for gripping the obstruction or the tissue part from inside}
- A61B 2017/22094: {for crossing total occlusions, i.e. piercing}
- A61B 2017/2215: {having an open distal end}
- A61F 2002/016: {made from wire-like elements}
- A61F 2230/0023: triangular
- A61F 2250/0043: differing in electric properties, e.g. in electrical conductivity, in galvanic properties
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

A medical device configured to perform an endovascular therapy can include an elongate manipulation member and an intervention member. The elongate manipulation member can include a distal end portion. The intervention member can include a proximal end portion and a mesh. The proximal end portion can be coupled with the distal end portion of the elongate manipulation member. The mesh can have a plurality of cells in a tubular configuration and being compressible to a collapsed configuration for delivery to an endovascular treatment site through a catheter and being self-expandable from the collapsed configuration to an expanded configuration. The mesh can include an anodic metal and a cathodic metal. The anodic metal and the cathodic metal can each form a fraction of a total surface area of the mesh.

## Claims

### Claim 1

A medical device configured to perform an endovascular therapy, the device comprising:
an elongate manipulation member comprising a distal end portion; and
an intervention member comprising:
a proximal end portion coupled to the distal end portion; and
a mesh having a plurality of cells, wherein an inwardly facing surface of the mesh is formed substantially only by an anodic metal, and an outwardly facing surface of the mesh is formed substantially only by a cathodic metal.

### Claim 2 (depends on 1)

The medical device of claim 1, wherein the anodic metal comprises a plurality of discrete portions of the anodic metal.

### Claim 3 (depends on 1)

The medical device of claim 1, wherein the anodic metal is contiguous.

### Claim 4 (depends on 1)

The medical device of claim 1, wherein the outwardly facing surface is configured to engage an interior surface of a catheter during delivery of the medical device through a lumen of the catheter, and an average coefficient of friction of the outwardly facing surface is less than an average coefficient of friction of the inwardly facing surface.

### Claim 5 (depends on 1)

The medical device of claim 1, wherein the outwardly facing surface is configured to engage an interior surface of a catheter during delivery of the medical device through a lumen of the catheter, and substantially none of the outwardly facing surface is formed by the anodic metal.

### Claim 6 (depends on 1)

The medical device of claim 1, wherein the anodic metal is in direct contact with the cathodic metal.

### Claim 7 (depends on 1)

The medical device of claim 1, wherein at least a portion of the anodic metal has a thickness of at least 2 μm.

### Claim 8 (depends on 1)

The medical device of claim 1, wherein the anodic metal comprises magnesium and the cathodic metal comprises nickel and titanium.

### Claim 9 (depends on 1)

The medical device of claim 1, wherein the mesh is rolled in a collapsed configuration such that a first portion and a second portion of the mesh are overlapped in at least one radial direction with a surface area of the first portion contacting a surface area of the second portion, and each of a surface area of the first portion and a surface area of the second portion comprises substantially no anodic metal.

### Claim 10 (depends on 1)

The medical device of claim 1, further comprising a temporary cover material that encapsulates at least a portion of the anodic metal.

### Claim 11 (depends on 10)

The medical device of claim 10, wherein the temporary cover material is erodible, dissolvable, degradable or absorbable in vivo.

### Claim 12 (depends on 11)

The medical device of claim 11, wherein the temporary cover material encapsulates substantially all of the anodic metal.

### Claim 13

A medical device configured to perform an endovascular therapy, the device comprising:
an intervention member comprising a mesh having a plurality of cells defining an inwardly facing surface and an outwardly facing surface, the mesh comprising means for galvanically assisting internal attachment of the mesh to a thrombus,
wherein the inwardly facing surface of the mesh is formed substantially only by an anodic metal, and the outwardly facing surface of the mesh is formed substantially only by a cathodic metal.

### Claim 14 (depends on 13)

The medical device of claim 13, wherein the means for galvanically assisting attachment of the mesh to the thrombus comprises the anodic metal and the cathodic metal.

### Claim 15 (depends on 13)

The medical device of claim 13, wherein the anodic metal comprises magnesium and the cathodic metal comprises nickel and titanium.

### Claim 16 (depends on 13)

The medical device of claim 13, wherein the anodic metal comprises a plurality of discrete portions of the anodic metal.

### Claim 17 (depends on 13)

The medical device of claim 13, wherein the anodic metal is contiguous.

### Claim 18 (depends on 13)

The medical device of claim 13, wherein the anodic metal is in direct contact with the cathodic metal.

### Claim 19 (depends on 13)

The medical device of claim 13, further comprising a temporary cover material that encapsulates at least a portion of the anodic metal.

### Claim 20 (depends on 19)

The medical device of claim 19, wherein the temporary cover material is erodible, dissolvable, degradable or absorbable in vivo.
