# US 10,499,925 B2 · Embolization device constructed from expansile polymer > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,499,925 B2 - Document ID: US10499925B2 - Status: Granted - Kind: B2 - Application number: 15/847,745 - Filed: 2017-12-19 - Published: 2018-04-26 - Granted: 2019-12-10 - Earliest claimed: 2006-06-15 - Assignees: MicroVention, Inc. - Applicants: MicroVention, Inc. - Inventors: Gregory M. Cruise; Michael Constant; Terrance Tran; Joseph Gulachenski - Web page: https://patentgrep.com/patent/US10499925B2 ## CPC - A61B 17/1219: {expandable in contact with liquids} - A61B 17/12113: {within an aneurysm} - A61B 17/1214: {Coils or wires} - A61B 17/12145: {having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526)} - A61B 17/12154: {having stretch limiting means} - A61B 17/12168: {having a mesh structure (A61B17/1214 takes precedence)} - A61L 31/00: Materials for other surgical articles {, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices (shape or structure of stent-grafts A61F2/07, of stents A61F2/82, of surgical gloves A61B42/00, of surgical drapes A61B46/00, of occluding devices A61B17/12022)} - A61L 31/022: {Metals or alloys} - A61L 31/041: {Mixtures of macromolecular compounds} - A61L 31/048: {obtained by reactions only involving carbon-to-carbon unsaturated bonds (A61L31/041 takes precedence)} - A61L 31/06: obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds {(A61L31/041 takes precedence)} - A61L 31/14: Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials} - A61L 31/145: {Hydrogels or hydrocolloids} - A61L 31/146: {Porous materials, e.g. foams or sponges} - A61L 2400/04: Materials for stopping bleeding - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) ## Abstract Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices. The devices may be comprised of novel expansile materials, novel infrastructure design, or both. The devices provided are very flexible and enable deployment with reduced or no damage to bodily tissues, conduits, cavities, etceteras. ## Claims ### Claim 1 An occlusion device comprising: an elongated, expansile element having a solid mass, that is flexible in an untreated state, consisting essentially of a poly(ethylene glycol) macromer and a pH sensitive monomer; and a carrier element comprising a plurality of loops forming a helical shape disposed around the expansile element, wherein the plurality of loops are spaced to form at least one gap and the at least one gap is between about 0.00025 inches and about 0.2 inches. ### Claim 2 (depends on 1) The occlusion device of claim 1, wherein the carrier element is between about 0.005 inches and about 0.035 inches in diameter. ### Claim 3 (depends on 1) The occlusion device of claim 1, wherein the carrier element is between about 0.0005 inches and about 0.01 inches in diameter. ### Claim 4 (depends on 1) The occlusion device of claim 1, wherein the carrier element is between about 0.008 inches and about 0.016 inches in diameter. ### Claim 5 (depends on 1) The occlusion device of claim 1, wherein the carrier element is between about 0.00075 inches and about 0.004 inches in diameter. ### Claim 6 (depends on 1) The occlusion device of claim 1, wherein the expansile element is between about 0.001 inches and about 0.03 inches in diameter before expansion. ### Claim 7 (depends on 1) The occlusion device of claim 1, wherein the expansile element is between about 0.002 inches and about 0.25 inches in diameter after expansion. ### Claim 8 (depends on 1) The occlusion device of claim 1, wherein the pH sensitive monomer is sodium acrylate. ### Claim 9 (depends on 1) The occlusion device of claim 1, wherein the expansile element is secured to the carrier element in a stretched configuration that is between about 125% and about 600% of its initial length. ### Claim 10 (depends on 1) The occlusion device of claim 1, wherein at least one gap is configured to allow the expansile element to expand through the at least one gap. ### Claim 11 (depends on 1) The occlusion device of claim 1, wherein the at least one gap has a distance of about 0.00025 inches to about 0.005 inches. ### Claim 12 (depends on 1) The occlusion device of claim 1, wherein the at least one gap is about 0.0013 inches. ### Claim 13 (depends on 1) The occlusion device of claim 1, wherein the carrier element is formed of a material including polyimide, nylon, polyester, polyglycolic acid, polylactic acid, PEEK, Teflon, carbon fiber or pyrolytic carbon, silicone, platinum, steel, tungsten, Nitinol, tantalum, titanium, or chromium-cobalt alloy. ### Claim 14 (depends on 1) The occlusion device of claim 1, wherein the carrier element is formed of platinum. ### Claim 15 (depends on 1) The occlusion device of claim 1, wherein the carrier element is formed of tungsten. ### Claim 16 (depends on 1) The occlusion device of claim 1, further including a stretch resistant member. ### Claim 17 (depends on 1) The occlusion device of claim 1, wherein the stretch resistant member is formed of a material including steel, nickel titanium, PET, PEEK, nylon, polytetrafluoroethylene, polyethylene, polyolefin, polyolefin elastomer, polypropylene, polylactic acid, or polyglycolic acid. ### Claim 18 (depends on 1) The occlusion device of claim 1, wherein the stretch resistant member is formed of PET. ### Claim 19 (depends on 1) The occlusion device of claim 1, wherein the stretch resistant member is formed of polyethylene.