# US 10,499,664 B2 · Fish feed formulation of Hypericum perforatum, Rosamarinus officianalis or a mixture thereof

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- Number: US 10,499,664 B2
- Document ID: US10499664B2
- Status: Granted
- Kind: B2
- Application number: 15/085,590
- Filed: 2016-03-30
- Published: 2016-10-06
- Granted: 2019-12-10
- Earliest claimed: 2015-03-31
- Assignees: Universidad de Santiago de Chile
- Applicants: Universidad De Santiago De Chile
- Inventors: Margarita Paz Montoya Kunsting; Marcelo Andrés Cortez San Martin; Claudio Antonio Acuña Castillo; Sophia Charlotte Mejias Medina; Viviana Andrea Ahumada Muñoz
- Web page: https://patentgrep.com/patent/US10499664B2

## CPC

- A23K 10/30: from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms (obtained by microbiological or biochemical processes, e.g. using yeasts or enzymes, A23K10/10)
- A23K 20/10: Organic substances
- A23K 20/111: Aromatic compounds
- A23K 50/80: for aquatic animals, e.g. fish, crustaceans or molluscs
- A61K 9/0056: {Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals}
- A61K 36/38: Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
- A61K 36/53: Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- Y02A 40/81: Aquaculture, e.g. of fish
- A23K: FODDER
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- Y02A: TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE

## Abstract

The present invention thus relates to a formulation comprising St. John's Wort (Hypericum perforatum, HP), rosemary (Rosmarinus officinalis) extracts or a mixture of both, to improve survival to stressful and pathogens events, and also the feed conversion factor (greater weight gain and growth by delivered food). All of this, without affecting the fish smoltification ability.

## Claims

### Claim 1

Method of enhancing gain in weight of cultured fish which comprises administering to said fish a formulation comprising St. John's Wort (Hypericum perforatum) extract, Rosmarinus officinalis (RO) extract or a mixture of both in an amount of from 1.5 mg/kg of fish to 15 mg/kg of fish for a period sufficient to enhance the weight gain of the fish.