Production of xylitol from glucose by a recombinant strain
AssigneeRoquette Freres
InventorsAstrid Schaefer, Melanie Diefenbacher, Yiming Chang, Sumire Honda Malca, Markus Schwab, Sophie Defretin, Tania Gerard, Arnaud Heysen, Friederike Thor
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Abstract
The present invention relates to a recombinant microbial host for the production of xylitol, the recombinant microbial host containing a nucleic acid sequence encoding an NAD+-specific D-arabitol 4-oxidoreductase (EC 1.1.1.11) using D-arabitol as substrate and producing D-xylulose as product, and a nucleic acid sequence encoding an NADPH-specific xylitol dehydrogenase using D-xylulose as substrate and producing xylitol as product.
Claims2
A recombinant Pichia ohmeri selected from strains I-4982, I-4960 and I-4981 deposited at the National Collection of Microorganism Cultures.
Dependencies are inferred from the claim text.