Loading patent…
OwnerScott Eugene Bucklin, Troy James Kaiser +3inventors
InventorsScott Eugene Bucklin, Troy James Kaiser, Jeremy Kroll, Philip Utley, Eric Martin Vaughn
Estimating the term…
The present invention relates to a porcine parvovirus (PPV) viral protein 2 (VP2) having at amino acid position 228 a glutamic acid residue or a glutamate residue, and/or at amino acid position 414 a serine residue, and/or at amino acid position 419 a glutamine residue, and/or at amino acid position 436 a threonine residue. Further, the present invention relates to immunogenic compositions comprising said PPV viral protein 2 (VP2). Furthermore, the present invention relates to methods for immunizing a subject comprising administering to such subject the immunogenic composition of the present invention. Moreover, the present invention relates to methods of treating or preventing clinical signs caused by PPV infection in a subject of need, the method comprising administering to the subject a therapeutically effective amount of an immunogenic composition according to the present invention.
A porcine parvovirus (PPV) viral protein 2 (VP2) comprising an isoleucine residue at amino acid position 25, a serine residue at amino acid position 36, an isoleucine residue at amino acid position 37, a glutamic acid residue or a glutamate residue at amino acid position 228, a serine residue at amino acid position 414, a glutamine residue at amino acid position 419, and a threonine residue at amino acid position 436, wherein amino acid position numbering refers to an amino acid sequence of wild type PPV VP2.
A PPV VP2 comprising an amino acid sequence having at least 99.6% sequence identity to SEQ ID NO. 2.
Dependencies are inferred from the claim text.