# US 10,481,232 B2 · Magnetic resonance imaging apparatus and magnetic resonance imaging method

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- Number: US 10,481,232 B2
- Document ID: US10481232B2
- Status: Granted
- Kind: B2
- Application number: 15/487,099
- Filed: 2017-04-13
- Published: 2018-10-18
- Granted: 2019-11-19
- Earliest claimed: 2017-04-13
- Assignees: Canon Medical Systems Corporation
- Applicants: Toshiba Medical Systems Corporation
- Inventors: Mitsue Miyazaki; Cheng Ouyang
- Web page: https://patentgrep.com/patent/US10481232B2

## CPC

- G01R 33/5605: {by transferring coherence or polarization from a spin species to another, e.g. creating magnetization transfer contrast [MTC], polarization transfer using nuclear Overhauser enhancement [NOE]}
- G01R 33/482: {using a Cartesian trajectory}
- G01R 33/4824: {using a non-Cartesian trajectory}
- G01R 33/546: {Interface between the MR system and the user, e.g. for controlling the operation of the MR system or for the design of pulse sequences}
- G01R 33/5619: {by temporal sharing of data, e.g. keyhole, block regional interpolation scheme for k-Space [BRISK]}
- G01R: MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES (indicating correct tuning of resonant circuits H03J3/12)

## Abstract

A magnetic resonance imaging apparatus according to an embodiment includes sequence control circuitry. The sequence control circuitry executes a first pulse sequence that acquires data by radial sampling. The sequence control circuitry executes a second pulse sequence a plurality of times by changing a frequency of magnetization transfer (MT) pulses, the second pulse sequence acquiring data by Cartesian sampling after applying an MT pulse.

## Claims

### Claim 1

A magnetic resonance imaging apparatus comprising:
sequence control circuitry configured to execute a first pulse sequence that acquires data by radial sampling and configured to execute a second pulse sequence a plurality of times by changing a frequency of magnetization transfer (MT) pulses, the second pulse sequence acquiring data by Cartesian sampling after applying an MT pulse, and
processing circuitry configured to calculate a spectrum based on data acquired from the first pulse sequence and the second pulse sequence.

### Claim 2 (depends on 1)

The magnetic resonance imaging apparatus according to claim 1, wherein the sequence control circuitry is further configured to apply a fat saturation pulse in the second pulse sequence.

### Claim 3 (depends on 1)

The magnetic resonance imaging apparatus according to claim 1, wherein
the processing circuitry is configured to calculate an area of a k-space in which data acquisition is performed by the Cartesian sampling, and
the sequence control circuitry is configured to acquire data by the Cartesian sampling in the area of the k-space calculated by the processing circuitry.

### Claim 4 (depends on 1)

The magnetic resonance imaging apparatus according to claim 1, wherein
the sequence control circuitry is configured to split the first pulse sequence into a plurality of times of acquisition, thereby executing the first pulse sequence.

### Claim 5 (depends on 1)

The magnetic resonance imaging apparatus according to claim 1, wherein
the sequence control circuitry is configured to split the Cartesian sampling in the second pulse sequence into a plurality of times of acquisition, thereby executing the second pulse sequence.

### Claim 6 (depends on 5)

The magnetic resonance imaging apparatus according to claim 5, wherein
the processing circuitry configured to calculate, based on information on a target to be imaged, how division of segments of a k-space is performed, the k-space being a k-space in which the Cartesian sampling is split into a plurality of times of acquisition and executed, and
the sequence control circuitry is configured to split, based on the division of the segments calculated by the processing circuitry, the Cartesian sampling in the second pulse sequence into a plurality of times of sampling, thereby executing the Cartesian sampling.

### Claim 7 (depends on 1)

The magnetic resonance imaging apparatus according to claim 1, wherein the spectrum indicates an amount of CEST effect.

### Claim 8 (depends on 7)

The magnetic resonance imaging apparatus according to claim 7, wherein the processing circuitry is configured to accept an input of a selection of a region of interest (ROI) from a user and configured to calculate the spectrum based on the input accepted.

### Claim 9 (depends on 1)

The magnetic resonance imaging apparatus according to claim 1, wherein the sequence control circuitry is configured to perform the radial sampling in the first pulse sequence by using golden-angle sampling pattern.

### Claim 10

A magnetic resonance imaging method executed in a magnetic resonance imaging apparatus including:
executing a first pulse sequence that acquires data by radial sampling;
executing a second pulse sequence a plurality of times by changing a frequency of magnetization transfer (MT) pulses, the second pulse sequence acquiring data by Cartesian sampling after applying an MT pulse; and
calculating a spectrum based on data acquired from the first pulse sequence and the second pulse sequence.