# US 10,478,637 B2 · System and method for limiting chemotherapy-induced alopecia

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- Number: US 10,478,637 B2
- Document ID: US10478637B2
- Status: Granted
- Kind: B2
- Application number: 15/143,475
- Filed: 2016-04-29
- Published: 2016-11-03
- Granted: 2019-11-19
- Earliest claimed: 2015-04-30
- Assignees: Hair Science Systems LLC
- Applicants: William R. Banker
- Inventors: William R. Banker
- Web page: https://patentgrep.com/patent/US10478637B2

## CPC

- A61N 5/0617: {Hair treatment}
- A61F 7/10: Cooling bags, e.g. ice-bags
- A61H 9/0078: {with intermittent or alternately inflated bladders or cuffs (mattresses for preventing bed-sores with alternated pressurized chambers A61G7/05776)}
- A61F 2007/0002: {Head or parts thereof}
- A61F 2007/0008: {Scalp}
- A61F 2007/0056: {for cooling}
- A61F 2007/0091: {inflatable}
- A61F 2007/0096: {with a thermometer}
- A61F 2007/0273: {with openings in the walls between the compartments serving as passageways for the filler}
- A61F 2007/0287: {Preventing negative effects of chemotherapy}
- A61H 2201/0214: cooled
- A61H 2201/0242: by a fluid circulating in the apparatus
- A61H 2201/10: with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy
- A61H 2205/021: Scalp
- A61N 5/067: using laser light
- A61N 2005/0652: {Arrays of diodes}
- A61N 2005/0662: {Visible light}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- A61H: PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY (electrotherapy, magnetotherapy, radiation therapy or ultrasound therapy A61N)

## Abstract

A cold cap adapted for connecting to a chiller unit for circulating chilled fluid through the cap. The cap is formed from at least three layers of material which are sealingly attached around their periphery so as to form a cooling fluid chamber, wherein the cap is configured to apply compression and cooling to the scalp.

## Claims

### Claim 1

A cold cap for use in limiting chemotherapy-induced hair loss in a patient, said cap adapted for connecting to a chiller unit for circulating chilled fluid through the cap and receiving pressurized air for supplying compression to the scalp of a patient, wherein said cap comprises:
at least three layers of fluid impermeable material which are sealingly attached around their periphery so as to form a cooling fluid chamber configured to cool the scalp when chilled fluid is circulated through the cooling fluid chamber, and an air chamber configured to apply compression to the scalp when pressurized air is supplied to the air chamber;
fluid inlet and outlet conduits in fluid communication with said cooling fluid chamber and configured for detachable attachment to a fluid outlet and a fluid inlet of the chiller unit;
air inlet tubing in communication with said air chamber;
a first internal seal that seals said at least three layers to one another, said first internal seal spaced inwardly of the sealed periphery of said at least three layers so as to provide additional support and define a serpentine flow pattern within said cooling fluid chamber, thereby defining a flow pattern by which chilled fluid can be circulated over and about the patient's head so as to provide generally uniform cooling of the patient's scalp; and
second and third internal seals located along opposite sides of said cap, said second and third internal seals extending inwardly from the sealed periphery of said at least three layers, such that each of said second and third internal seals together with an adjacent portion of said sealed periphery define regions within said cap that are not in fluid communication with said cooling fluid chamber;
wherein said cap is adapted to be worn by the patient such that the cap extends in surrounding relationship to and conforming to the patient's scalp, with said regions not in fluid communication with said cooling fluid chamber extending over the patient's ears such that cooling is not applied to the patient's ears during use.

### Claim 2 (depends on 1)

The cold cap of claim 1, wherein said air chamber is located between a first layer and a second layer of said at least three layers, and said cooling fluid chamber is located between said second layer and a third layer of said at least three layers, and further comprising a plurality of columnar seals extending between and connecting said second and third layers, wherein said columnar seals act as support columns and break up water flow through said fluid cooling chamber.