# US 10,478,531 B2 · Methods and materials for treating blood vessels

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 10,478,531 B2
- Document ID: US10478531B2
- Status: Granted
- Kind: B2
- Application number: 15/708,406
- Filed: 2017-09-19
- Published: 2018-12-27
- Granted: 2019-11-19
- Earliest claimed: 2017-06-22
- Applicants: Gary M. Petrucci
- Inventors: Gary M. Petrucci
- Web page: https://patentgrep.com/patent/US10478531B2

## CPC

- A61L 29/005: {Ingredients of undetermined constitution or reaction products thereof}
- A61L 31/16: Biologically active materials, e.g. therapeutic substances {(A61L31/047 takes precedence)}
- A61F 2/07: Stent-grafts
- A61L 29/085: {Macromolecular materials}
- A61L 29/16: Biologically active materials, e.g. therapeutic substances {(A61L29/048 takes precedence)}
- A61L 31/08: Materials for coatings
- A61M 25/104: {used for angioplasty}
- A61L 27/3804: {characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells}
- A61L 31/148: {Materials at least partially resorbable by the body}
- A61L 2300/416: Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
- A61M 2025/105: {having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes}
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

This document provides methods and materials for treating a mammal (e.g., a human) having one or more stenotic blood vessels. For example, amnion coated balloons that can be used in balloon angioplasty are provided.

## Claims

### Claim 1

An angioplasty balloon catheter comprising a stent-less angioplasty balloon coated with an amnion tissue preparation.

### Claim 2 (depends on 1)

The angioplasty balloon catheter of claim 1, wherein said amnion tissue preparation has viable cells.

### Claim 3 (depends on 1)

The angioplasty balloon catheter of claim 1, wherein said amnion tissue preparation lacks viable cells.

### Claim 4 (depends on 1)

The angioplasty balloon catheter of claim 1, wherein said amnion tissue preparation is a dried amnion tissue preparation.

### Claim 5 (depends on 4)

The angioplasty balloon catheter of claim 4, wherein said dried amnion tissue preparation has a water content that is less than about 8 percent.