# US 10,478,390 B2 · Use of glycosides to increase hair mass

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- Number: US 10,478,390 B2
- Document ID: US10478390B2
- Status: Granted
- Kind: B2
- Application number: 15/769,138
- Filed: 2016-10-20
- Published: 2018-10-25
- Granted: 2019-11-19
- Earliest claimed: 2015-10-20
- Assignees: L'oreal
- Applicants: L'oreal
- Inventors: Sébastien Thibaut; Maria Dalko
- Web page: https://patentgrep.com/patent/US10478390B2

## CPC

- A61K 8/602: {Glycosides, e.g. rutin}
- A61Q 7/00: Preparations for affecting hair growth
- A61K 8/06: Emulsions
- A61K 8/42: Amides
- A61K 8/44: Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K 8/46: containing sulfur (A61K8/44 takes precedence)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

This invention relates to the cosmetic use of at least one glycoside chosen from glycosides having the following general formula (I): Sacc-(CH2)i—X—R in order to increase the hair mass.

## Claims

### Claim 1

A cosmetic method for increasing the diameter of hair fiber of an individual desiring such, which comprises applying to the scalp of said individual in order to increase the diameter of hair fiber at least one glycoside have the following formula (II):
X being —O—, —C(Ra)=N—O— or —C(Rb)(Rc)-
i is 0 or 1;
Ra representing H or a linear or branched (C1-C6)alkyl group,
Rb and Rc, are identical or different, representing H or a group chosen from the group consisting of hydroxy, alkoxy(C1-C6), alkoxy(C1-C6)amino, alkoxy(C1-C6)ammonium, alkoxy(C1-C6)-diamino, amino, (C1-C6)alkylamino, di((C1-C6)alkyl)amino, hydroxy(C1-C6)alkylamino, di(hydroxy(C1-C6)alkyl)amino, and (hetero)arylamino groups;
R represents a (C1-C10)alkyl, linear or branched, said alkyl group being possibly substituted by at least one substituent chosen from the group consisting of ORa, —C(O)OH and —C(O)OR″2, R″2 being a linear or branched (C1-C4)alkyl group;
or R represents a (C1-C4)alkyl(C6-C10)aryl group, said aryl group being optionally substituted by at least one substituent ORe, Re representing H or a linear or branched (C1-C6)alkyl group;
the bond representing a bond of a C-anomeric nature, which is α or β,
as well as the salts thereof, the solvates thereof and the optical and geometric isomers thereof.

### Claim 2 (depends on 1)

The cosmetic method according to claim 1, wherein X is —O—, —C(CH3)═N—O— or —CH(OH)—.

### Claim 3 (depends on 1)

The cosmetic method according to claim 1, wherein the glycoside is C-β-D-xylopyranoside-2-hydroxy-propane.

### Claim 4 (depends on 1)

The cosmetic method according to claim 1, wherein the glycoside is present in a cosmetic composition, at a rate of about 0.0001% to about 25% by weight with respect to the total weight of said composition.

### Claim 5 (depends on 1)

The cosmetic method according to claim 1, wherein the glycoside is implemented within a cosmetic composition adapted for topical administration.

### Claim 6 (depends on 5)

The cosmetic method according to claim 5, wherein the composition is in the form of a suspension, gel, emulsion, shampoo, unrinsed lotion or foam.

### Claim 7 (depends on 1)

The cosmetic method according to claim 1, for increasing the volume of the hair and/or hair mass.

### Claim 8 (depends on 2)

The cosmetic method according to claim 2, wherein the glycoside is C-β-D-xylopyranoside-2-hydroxy-propane.

### Claim 9 (depends on 2)

The cosmetic method according to claim 2, wherein the glycoside is present in a cosmetic composition, at a rate of about 0.0001% to about 25% by weight with respect to the total weight of said composition.

### Claim 10 (depends on 3)

The cosmetic method according to claim 3, wherein the glycoside is present in a cosmetic composition, at a rate of about 0.0001% to about 25% by weight with respect to the total weight of said composition.

### Claim 11 (depends on 1)

The cosmetic method according to claim 1, wherein the composition is applied to hair follicles of said individual.