# US 10,478,335 B2 · Intraocular delivery devices and methods therefor > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,478,335 B2 - Document ID: US10478335B2 - Status: Granted - Kind: B2 - Application number: 16/057,758 - Filed: 2018-08-07 - Published: 2018-12-06 - Granted: 2019-11-19 - Earliest claimed: 2012-04-02 - Assignees: OcuJect, LLC - Applicants: OcuJect, LLC - Inventors: Leonid E. Lerner - Web page: https://patentgrep.com/patent/US10478335B2 ## CPC - A61F 9/00736: {Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments (A61F9/008 takes precedence)} - A61F 9/0017: {implantable in, or in contact with, the eye, e.g. ocular inserts} - A61F 9/0026: {Ophthalmic product dispenser attachments to facilitate positioning near the eye} - A61M 5/3145: {Filters incorporated in syringes} - A61M 5/3243: {being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel (devices for protecting guide needles in combination with catheters A61M25/0612)} - A61M 5/38: using hydrophilic or hydrophobic filters - A61M 5/46: having means for controlling depth of insertion - A61M 2210/0612: Eyes - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on a removable injector attachment or on a portion of the injection device housing. Other devices may include a filter for the removal of air, infectious agents, and/or other particulate matter from the composition before the composition is injected into the eye. Related methods and systems comprising the devices are also described. ## Claims ### Claim 1 A method of loading a drug into a drug reservoir, comprising: providing a drug vial comprising a stopper and the drug within a vial cavity; providing a drug reservoir injector comprising a distal port and the drug reservoir; loading the drug reservoir with the drug from the vial through a needle assembly; removing the needle assembly from the drug reservoir system; and connecting the drug reservoir injector with an injector attachment comprising: a needle hub comprising a tubular body and comprising an input port on its proximal end for removable connection to the injector, and a distal stop surface; a needle comprising a proximal portion and a distal portion, the proximal portion of the needle housed within the tubular body of the needle hub, and the distal end of the needle extending distally beyond the needle hub; a rigid slidable shield comprising a distal opening, a proximal opening, and an uninterrupted sidewall between the distal opening and the proximal opening configured to protect the sterility of the needle and operatively coupled to the needle hub and having a fixed axial dimension, the slidable shield configured for axial movement along the needle hub between the input port and the distal stop surface and configured such that the needle is completely circumscribed by the shield and the distal portion of the needle hub when the shield is in a first, distal position with respect to the needle hub, and the distal portion of the needle extends distally beyond the shield when the shield is in a second, proximal position with respect to the needle hub, a patient contact surface, the patient contact surface comprising a perimeter and located at a distal end of the slidable shield; and a lever attached to the needle hub, the lever configured to prevent axial movement of the slidable shield and to maintain the shield in the first, distal position with respect to the needle hub by a locking shoulder at a distal end of the lever contacting a proximal end wall of the slidable shield thereby preventing proximal movement of the shield away from the first, distal position. ### Claim 2 (depends on 1) The method of claim 1, wherein the input port comprises a luer lock. ### Claim 3 (depends on 1) The method of claim 1, wherein the drug reservoir comprises a syringe.