# US 10,478,289 B2 · Replacement valve and anchor > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,478,289 B2 - Document ID: US10478289B2 - Status: Granted - Kind: B2 - Application number: 15/675,978 - Filed: 2017-08-14 - Published: 2017-11-30 - Granted: 2019-11-19 - Earliest claimed: 2003-12-23 - Assignees: Boston Scientific Scimed, Inc. - Applicants: Boston Scientific Scimed, Inc. - Inventors: Amr Salahieh; Brian D. Brandt; Dwight P. Morejohn; Ulrich R. Haug; Jean-Pierre Dueri; Hans F. Valencia; Robert A. Geshlider - Web page: https://patentgrep.com/patent/US10478289B2 ## CPC - A61F 2/2412: {with soft flexible valve members, e.g. tissue valves shaped like natural valves} - A61F 2/2418: {Scaffolds therefor, e.g. support stents} - A61F 2/2439: {Expansion controlled by filaments} - A61F 2220/0016: with sharp anchoring protrusions, e.g. barbs, pins, spikes - A61F 2220/005: using adhesives - A61F 2220/0058: soldered or brazed or welded - A61F 2230/005: Rosette-shaped, e.g. star-shaped - A61F 2230/0054: V-shaped - A61F 2230/0065: toroidal, e.g. ring-shaped, doughnut-shaped - A61F 2230/0078: hyperboloidal - A61F 2250/0069: Sealing means - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) ## Abstract Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration. ## Claims ### Claim 1 An implantable prosthetic heart valve, comprising: a stent having a distal inflow region defining a distal end of the stent and a distalmost inflow outer diameter, a central region having a central outer diameter, and a proximal outflow region defining a proximal end of the stent and a proximalmost outflow outer diameter; and a plurality of leaflets coupled to the stent; wherein the proximalmost outflow outer diameter is greater than the central outer diameter; wherein the proximalmost outflow outer diameter is greater than the distalmost inflow outer diameter; and wherein the distalmost inflow outer diameter is greater than the central outer diameter. ### Claim 2 (depends on 1) The implantable prosthetic heart valve of claim 1, wherein the stent includes a self-expanding material. ### Claim 3 (depends on 1) The implantable prosthetic heart valve of claim 1, wherein the stent includes a nickel-titanium alloy. ### Claim 4 (depends on 1) The implantable prosthetic heart valve of claim 1, wherein the stent includes a cobalt-chromium alloy. ### Claim 5 (depends on 1) The implantable prosthetic heart valve of claim 1, further comprising a sealing member coupled to the stent. ### Claim 6 (depends on 5) The implantable prosthetic heart valve of claim 5, wherein the sealing member includes a fabric. ### Claim 7 (depends on 5) The implantable prosthetic heart valve of claim 5, wherein the sealing member includes a pocket. ### Claim 8 (depends on 5) The implantable prosthetic heart valve of claim 5, wherein the sealing member includes a sac. ### Claim 9 An implantable prosthetic heart valve, comprising: a stent having a distal inflow region defining a distal end of the stent and a distalmost inflow outer diameter, a central region having a central outer diameter, and a proximal outflow region defining a proximal end of the stent and a proximalmost outflow outer diameter; a plurality of leaflets coupled to the stent; wherein the proximalmost outflow outer diameter is greater than the distalmost inflow outer diameter, the central outer diameter, or both; a sealing member coupled to the stent. ### Claim 10 (depends on 9) The implantable prosthetic heart valve of claim 9, wherein the sealing member is coupled to an outer surface of the stent. ### Claim 11 (depends on 9) The implantable prosthetic heart valve of claim 9, wherein at least a portion of the sealing member is disposed along the central region. ### Claim 12 (depends on 9) The implantable prosthetic heart valve of claim 9, wherein the stent includes a self-expanding material. ### Claim 13 (depends on 9) The implantable prosthetic heart valve of claim 9, wherein the stent includes a nickel-titanium alloy. ### Claim 14 (depends on 9) The implantable prosthetic heart valve of claim 9, wherein the stent includes a cobalt-chromium alloy. ### Claim 15 (depends on 9) The implantable prosthetic heart valve of claim 9, wherein the sealing member includes a fabric. ### Claim 16 (depends on 9) The implantable prosthetic heart valve of claim 9, wherein the sealing member includes a pocket. ### Claim 17 (depends on 9) The implantable prosthetic heart valve of claim 9, wherein the sealing member includes a sac. ### Claim 18 An implantable prosthetic heart valve, comprising: an expandable frame having a distal inflow region defining a distal end of the expandable frame and a distalmost inflow outer diameter, a central region having a central outer diameter, and a proximal outflow region defining a proximal end of the expandable frame and a proximalmost outflow outer diameter; a plurality of leaflets coupled to the expandable frame; wherein the proximalmost outflow outer diameter is greater than the central outer diameter; wherein the proximalmost outflow outer diameter is greater than the distalmost inflow outer diameter; wherein the distalmost inflow outer diameter is greater than the central outer diameter; and a sealing member coupled to an outer surface of the expandable frame. ### Claim 19 (depends on 18) The implantable prosthetic heart valve of claim 18, wherein the sealing member includes a fillable region. ### Claim 20 (depends on 18) The implantable prosthetic heart valve of claim 18, wherein the sealing member is designed to change shape and conform to a target region when the expandable frame is expanded.