# US 10,478,277 B2 · Bioabsorbable mesh for surgical implants > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,478,277 B2 - Document ID: US10478277B2 - Status: Granted - Kind: B2 - Application number: 15/980,114 - Filed: 2018-05-15 - Published: 2018-09-13 - Granted: 2019-11-19 - Earliest claimed: 2010-02-16 - Assignees: Boston Scientific Scimed, Inc. - Applicants: Boston Scientific Scimed, Inc. - Inventors: Edouard A. Koullick; Balkrishna S. Jadhav; Robert C. Grant - Web page: https://patentgrep.com/patent/US10478277B2 ## CPC - A61F 2/0022: {placed deep in the body opening (occluding blood vessels by internal devices A61B17/12022)} - A61F 2/0045: {Support slings} - A61F 2/0063: {Implantable repair or support meshes, e.g. hernia meshes} - A61L 31/041: {Mixtures of macromolecular compounds} - A61L 31/06: obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds {(A61L31/041 takes precedence)} - A61L 31/148: {Materials at least partially resorbable by the body} - A61F 2002/0068: {having a special mesh pattern} - A61F 2210/0004: bioabsorbable - A61F 2220/0008: Fixation appliances for connecting prostheses to the body - A61F 2250/0031: made from both resorbable and non-resorbable prosthetic parts, e.g. adjacent parts - A61F 2310/00389: The prosthesis being coated or covered with a particular material - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) ## Abstract Described are methods, devices, and systems related to pelvic implants, including implants that include absorbable and non-absorbable materials. ## Claims ### Claim 1 An implantable mesh comprising: a plurality of absorbable fibers; a plurality of non-absorbable fibers, the plurality of absorbable fibers being aligned in a first direction and the plurality of non-absorbable fibers i-s being aligned in a second direction, the second direction being substantially perpendicular to the first direction, to form openings between the plurality of absorbable fibers and the plurality of non-absorbable fibers, the plurality of absorbable fibers being interwoven or knitted with the plurality of non-absorbable fibers to form a mesh structure, the plurality of absorbable fibers being configured to degrade after implantation into a human subject; and an absorbable polymer, the absorbable polymer being located at least some of the openings. ### Claim 2 (depends on 1) The mesh according to claim 1, wherein the plurality of absorbable fibers include a polymer selected from a group consisting of polyhydroxyalkanoate, poly-L-lactic acid, polyanhydride, poly capro lactone, polyglycolic acid, poly-L-lactic acid, poly-D-L-lactic acid, polydioxanone, polyhydroxyalkanoate, polyphosphate ester, and combinations thereof. ### Claim 3 (depends on 1) The mesh according to claim 1, wherein e the plurality of absorbable fiber are paired with a non-absorbable fiber to form a fiber pair strand, and the mesh includes an interwoven or knitted fiber pair strands. ### Claim 4 (depends on 3) The mesh according to claim 3, further comprising a weave including one of: a plurality of fiber pair strands in a weft direction, a plurality of fiber pair strands in a warp direction, or a plurality of fiber pair strands in a weft direction and a plurality of fiber pair strands in a warp direction. ### Claim 5 (depends on 4) The mesh according to claim 4, wherein a relative amount of absorbable fibers per non-absorbable fibers in the weft direction is either greater than or less than a relative amount of absorbable fibers per non-absorbable fibers in the warp direction. ### Claim 6 (depends on 5) The mesh according to claim 5, wherein the weave includes weft fibers and warp fibers, wherein the plurality of absorbable fibers are included in the weft fibers or in the warp fibers, but not in both the weft fibers and the warp fibers. ### Claim 7 (depends on 1) The mesh according to claim 1, further comprising fibers in a weft direction, fibers in a warp direction, and fibers in a direction different from the weft direction and different from the warp direction. ### Claim 8 An implantable mesh comprising: a plurality of weft strands extending in a weft direction and a plurality of waft strands extending in a warp direction, the plurality of weft strands and the plurality of waft strands being non-absorbable fibers and interwoven or knitted to produce a porous mesh; and an absorbable polymer, wherein the absorbable polymer is located at intersections of the plurality of weft strands and the plurality of waft strands, wherein the absorbable polymer is configured to degrade after implantation into a human subject. ### Claim 9 (depends on 8) The mesh according to claim 8, wherein the absorbable polymer is selected from a group consisting of polyhydroxyalkanoate, poly-L-lactic acid, poly anhydride, polycaprolactone, polyglycolic acid, poly-L-lactic acid, poly-D-L-lactic acid, polydioxanone, polyhydroxyalkanoate, polyphosphate ester, and combinations thereof. ### Claim 10 (depends on 8) The mesh according to claim 8, wherein the plurality of weft strands and the plurality of waft strands are coated with the absorbable polymer. ### Claim 11 (depends on 10) A method of treating a pelvic condition by supporting a tissue of a pelvic region, the method comprising providing an implant including the mesh according to claim 10, and implanting the implant in a patient to support a tissue of a pelvic region. ### Claim 12 A method of treating a pelvic condition by supporting a tissue of a pelvic region, the method comprising: providing an implant including a mesh, the mesh including: a plurality of absorbable fibers; and a plurality of non-absorbable fibers, the plurality of absorbable fibers being aligned in a first direction and the plurality of non-absorbable fibers being aligned in a second direction, the second direction being substantially perpendicular to the first direction, to form openings between the plurality of absorbable fibers and the plurality of non-absorbable fibers, the plurality of absorbable fiber being interwoven or knitted with the plurality of non-absorbable fibers to form a mesh structure, the plurality of absorbable fibers being configured to degrade after implantation into a human subject; and an absorbable polymer, the absorbable polymer being located at least some of the openings; and implanting the mesh in a patient to support a tissue of a pelvic region. ### Claim 13 (depends on 12) The method according to claim 12, wherein the plurality of absorbable fibers comprise polymer selected from the group consisting of polyhydroxyalkanoate, poly-L-lactic acid, polyanhydride, polycaprolactone, polyglycolic acid, poly-L-lactic acid, poly-D-L-lactic acid, polydioxanone, polyhydroxyalkanoate, polyphosphate ester, and combinations thereof. ### Claim 14 A method of treating a pelvic condition by supporting tissue of a pelvic region, the method comprising providing an implant including a mesh, the mesh including: a plurality of weft strands extending in a weft direction and a plurality of waft strands extending in a warp direction, the plurality of weft strands and the plurality of waft strands being non-absorbable fibers and interwoven or knitted to produce a porous mesh; and an absorbable polymer, wherein the absorbable polymer is located at intersections of the plurality of weft strands and the plurality of waft strands, implanting the implant in a patient to support a tissue of a pelvic region. ### Claim 15 (depends on 14) The method according to claim 14, wherein the absorbable polymer is selected from a group consisting of polyhydroxyalkanoate, poly-L-lactic acid, polyanhydride, polycaprolactone, polyglycolic acid, poly-L-lactic acid, poly-D-L-lactic acid, polydioxanone, polyhydroxyalkanoate, polyphosphate ester, and combinations thereof. ### Claim 16 (depends on 15) The method according to claim 15, further comprising: creating an incision that allows access to a region of tissue of the pelvic floor, providing the implant to the region of tissue of the pelvic floor, the implant comprising a tissue support portion and an elongate end portion, passing the implant through the incision and placing the tissue support portion at the region of pelvic floor tissue, placing the elongate end portion at a location to support the tissue support portion, and positioning the tissue support portion at the region of the pelvic floor tissue in a manner to cause the tissue support portion to support the tissue of the pelvic floor tissue. ### Claim 17 (depends on 16) The method according to claim 16, wherein the tissue support portion comprises absorbable polymer and non-absorbable polymer. ### Claim 18 (depends on 17) The method according to claim 17, wherein the elongate end portion comprises absorbable polymer and non-absorbable polymer. ### Claim 19 (depends on 1) The mesh according to claim 1, wherein the absorbable polymer is disposed at a non-perpendicular angle with respect to the plurality of absorbable fibers and the plurality of non-absorbable fibers. ### Claim 20 (depends on 12) The method according to claim 12, wherein the absorbable polymer is disposed at a non-perpendicular angle with respect to the plurality of absorbable fibers and the plurality of non-absorbable fibers.