# US 10,478,212 B2 · Method and system for harvesting biological tissue

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- Number: US 10,478,212 B2
- Document ID: US10478212B2
- Status: Granted
- Kind: B2
- Application number: 14/957,846
- Filed: 2015-12-03
- Published: 2016-10-27
- Granted: 2019-11-19
- Earliest claimed: 2015-04-22
- Assignees: Medline Industries, Inc.
- Applicants: Medline Industries, Inc.
- Inventors: Marvin A. Guiles; Denis Labombard; Charles Sidoti; Philip S. Levin; Thomas Swyst; Sameer Sabir
- Web page: https://patentgrep.com/patent/US10478212B2

## CPC

- A61B 17/32053: {Punch like cutting instruments, e.g. using a cylindrical or oval knife (A61B17/326 takes precedence; trepans A61B17/1695)}
- A61B 10/0233: {Pointed or sharp biopsy instruments}
- A61B 17/3205: Excision instruments
- A61B 17/322: Skin grafting apparatus
- A61B 17/3421: {Cannulas}
- A61B 50/30: Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments (for wound clamps A61B17/10; for ligaturing clips A61B17/122; packages or dispensers for surgical gloves or finger-stalls A61B42/40)
- B21G 1/08: of hollow needles or needles with hollow end, e.g. hypodermic needles, larding-needles (B21G1/10 takes precedence)
- A61B 5/150022: {for capillary blood or interstitial fluid}
- A61B 5/150083: {by vibration, e.g. ultrasound}
- A61B 5/150282: {for piercing elements, e.g. blade, lancet, canula, needle}
- A61B 5/150305: {Packages specially adapted for piercing devices or blood sampling devices}
- A61B 5/150396: {Specific tip design, e.g. for improved penetration characteristics}
- A61B 5/150503: {Single-ended needles (hollow piercing element tip design A61B5/150396)}
- A61B 5/15142: {Devices intended for single use, i.e. disposable}
- A61B 17/3403: {Needle locating or guiding means}
- A61B 2017/0023: {disposable}
- A61B 2017/00367: {Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like}
- A61B 2017/00477: {Coupling (A61B2017/0046 takes precedence)}
- A61B 2017/00526: {Methods of manufacturing}
- A61B 2017/00747: {Dermatology}
- A61B 2017/00969: {used for transplantation}
- A61B 2017/320064: {with tissue or sample retaining means}
- A61B 2017/3225: {with processing of harvested tissue}
- A61B 2050/0065: {Peelable cover}
- A61B 2090/065: {for measuring contact or contact pressure}
- A61B 2090/067: {for measuring angles}
- A61B 2090/0807: {Indication means}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- B21G: MAKING NEEDLES, PINS OR NAILS OF METAL

## Abstract

In one aspect, the dual bevel needle can include a hollow tube having a proximal end, a distal end, a first lateral side, and a second lateral side opposite the first lateral side; a first needle point at the distal end of the hollow tube; a second point at the distal end of the hollow tube; a first bevel on each of the first lateral side and the second lateral side, the first bevel comprising a first bevel angle relative to a longitudinal axis of the tube; and a second bevel on each of the first lateral side and the second lateral side, the second bevel having a second bevel angle relative to the longitudinal axis of the tube, wherein the first and second bevels each form a portion of an ellipse, the ellipse having an inner cutting edge and terminating in the first and second needle points at the distal end of the tube, the second bevel angle being shallower than the first bevel angle, the second bevel being located adjacent the proximal end of the first bevel, and the inner cutting edge converging to a narrow heel.

## Claims

### Claim 1

A method for manufacturing hollow needles, the method comprising the steps of:
a. stamping a needle design into a sheet of material, wherein the needle design comprises a row of a plurality of hollow needles to be formed and a carrier, wherein the needle design of each of the plurality of hollow needles comprises a plurality of needle tips and at least one narrow heel;
b. processing the stamped needle design, including sharpening the plurality of needle tips and the at least one narrow heel; and
c. rolling the stamped, processed needle design to form the row of hollow needles wherein each hollow needle comprises a plurality of sharp tips, and at least one sharp narrow heel and wherein each needle remains attached to the carrier.

### Claim 2 (depends on 1)

The method of claim 1, wherein the needle design of each of the plurality of hollow needles comprises at least three needle tips, and wherein each hollow needle of the row of hollow needles comprises at least three tips.

### Claim 3 (depends on 1)

The method of claim 1, wherein the sharpening comprises etching.

### Claim 4 (depends on 1)

The method of claim 1, wherein the sharpening comprises grinding.

### Claim 5 (depends on 1)

The method of claim 1, wherein the sharpening comprises electropolishing.

### Claim 6 (depends on 1)

The method of claim 1, wherein rolling the stamped, processed needle design forms a central lumen of each hollow needle of the row of hollow needles, the central lumen having a diameter of less than about 1 mm.

### Claim 7 (depends on 1)

The method of claim 1, wherein rolling the stamped, processed needle design forms a central lumen of each hollow needle of the row of hollow needles, the central lumen having a diameter of less than about 0.8 mm.

### Claim 8 (depends on 1)

The method of claim 1, wherein the material comprises steel.

### Claim 9 (depends on 1)

The method of claim 1, wherein the material comprises plastic.

### Claim 10 (depends on 1)

The method of claim 1 further comprising:
d. forming a two dimensional array of hollow needles, the two dimensional array comprising a plurality of rows of hollow needles and carriers.

### Claim 11 (depends on 10)

The method of claim 10 wherein the two dimensional array comprises about 300 hollow needles.

### Claim 12 (depends on 1)

The method of claim 1, further comprising:
d. removing the carrier from the row of hollow needles.

### Claim 13 (depends on 12)

The method of claim 12, further comprising:
e. forming a plurality of rows of hollow needles into a two dimensional array of hollow needles.

### Claim 14 (depends on 1)

The method of claim 1, wherein rolling the stamped, processed needle design forms each hollow needle of the row of needles to be cylindrical.

### Claim 15 (depends on 1)

The method of claim 1, wherein rolling the stamped, processed needle design forms each hollow needle of the row of hollow needles to be non-cylindrical.

### Claim 16 (depends on 1)

The method of claim 1, wherein rolling the stamped, processed needle design forms a cross-section of each hollow needle of the row of hollow needles to be square.

### Claim 17 (depends on 1)

The method of claim 1, wherein rolling the stamped, processed needle design forms a cross-section of each hollow needle of the row of hollow needles to be oval.

### Claim 18 (depends on 1)

The method of claim 1, wherein rolling the stamped, processed needle design forms a cross-section of each hollow needle of the row of hollow needles to be circular.

### Claim 19 (depends on 1)

The method of claim 1, wherein rolling the stamped, processed needle design forms a cross-section of each hollow needle of the row of hollow needles to be a polygon.

### Claim 20 (depends on 1)

The method of claim 1, wherein the at least one narrow heel comprises two heels.

### Claim 21 (depends on 6)

The method of claim 6, wherein a width of each narrow heel is less than 15% of the diameter of the central lumen.