# US 10,478,168 B2 · Device and method for treatment of incision or hernia > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,478,168 B2 - Document ID: US10478168B2 - Status: Granted - Kind: B2 - Application number: 13/294,222 - Filed: 2011-11-11 - Published: 2012-03-08 - Granted: 2019-11-19 - Earliest claimed: 2011-11-11 - Assignees: LifeCell Corporation - Applicants: Wenquan Sun; Gary Monteiro - Inventors: Wenquan Sun; Gary Monteiro - Web page: https://patentgrep.com/patent/US10478168B2 ## CPC - A61B 17/0057: {Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect (sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009)} - A61F 2/0063: {Implantable repair or support meshes, e.g. hernia meshes} - A61L 31/005: {Ingredients of undetermined constitution or reaction products thereof} - A61B 17/0469: {Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery} - A61B 2017/00606: {Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) ## Abstract Devices and methods for treating an abdominal incision or hernia are described. An implant for the restoration or prophylactic treatment of an abdominal wall comprises an elongate element and at least one sheet connected to the elongate element along a longitudinal axis of the elongate element. The elongate element is positioned along the line of incision, and the at least one sheet is secured to the abdominal muscles surrounding the incision. ## Claims ### Claim 1 A device for treating an incision, hernia, or abdominal wall defect, comprising: an elongate element having a first longitudinal axis; and at least one sheet connected to the elongate element along the first longitudinal axis; wherein the at least one sheet comprises an acellular dermal tissue matrix derived from porcine dermis having a Young's modulus within a range of 49.5 MPa to 94.7 MPa. ### Claim 2 (depends on 1) The device of claim 1, wherein the at least one sheet is connected to the elongate element along an approximate midline of the sheet. ### Claim 3 (depends on 1) The device of claim 1, wherein the tissue is from an α1,3-galactosyltransferase (α1,3GT) deficient pig. ### Claim 4 (depends on 1) The device of claim 1, wherein the elongate element comprises an acellular dermal tissue matrix. ### Claim 5 (depends on 4) The device of claim 4, wherein the elongate element comprising the acellular dermal tissue matrix is rolled concentrically into a cylindrical structure. ### Claim 6 (depends on 1) The device of claim 1, wherein the elongate element comprises a piece of acellular connective tissue. ### Claim 7 (depends on 6) The device of claim 6, wherein the connective tissue is a tendon. ### Claim 8 (depends on 6) The device of claim 6, wherein the connective tissue is a ligament. ### Claim 9 (depends on 1) The device of claim 1, wherein the at least one sheet comprises multiple superimposed sheets. ### Claim 10 (depends on 1) The device of claim 1, wherein the at least one sheet is divided into two halves when connected to the elongate element. ### Claim 11 (depends on 1) The device of claim 1, wherein the at least one sheet is connected to the elongate element using surgical sutures. ### Claim 12 (depends on 1) The device of claim 1, wherein the biomechanical strength of the at least one sheet is equal to that of the elongate element. ### Claim 13 A method of closing a midline incision, comprising the steps of: providing an implant comprising an elongate element having a first longitudinal axis and at least one sheet connected to the elongate element along the first longitudinal axis, wherein the at least one sheet comprises an acellular dermal tissue matrix derived from porcine dermis having a Young's modulus within a range of 49.5 MPa to 94.7 MPa; positioning the elongate element along the midline incision; and positioning the at least one sheet on at least one of an anterior side and a posterior side of a rectus abdominis muscle surrounding the midline incision. ### Claim 14 (depends on 13) The method of claim 13, further comprising the step of creating spaces on the anterior or posterior sides of the rectus abdominis muscle for placement of the at least one sheet. ### Claim 15 (depends on 13) The method of claim 13, further comprising the step of suturing the at least one sheet to the rectus abdominis muscle. ### Claim 16 (depends on 13) The method of claim 13, wherein the at least one sheet is inserted between an anterior layer of fascia and the rectus abdominis muscle. ### Claim 17 (depends on 13) The method of claim 13, wherein the at least one sheet is inserted between a posterior layer of fascia and the rectus abdominis muscle. ### Claim 18 (depends on 13) The method of claim 13, wherein the at least one sheet is inserted over an anterior layer of fascia. ### Claim 19 (depends on 13) The method of claim 13, wherein the at least one sheet is inserted below a posterior layer of fascia. ### Claim 20 (depends on 13) The method of claim 13, wherein the acellular dermal tissue matrix is treated to remove antigens that are immunogenic to a human recipient. ### Claim 21 (depends on 13) The method of claim 13, wherein the elongate element comprises a piece of acellular connective tissue. ### Claim 22 (depends on 21) The method of claim 21, wherein the connective tissue comprises a tendon. ### Claim 23 (depends on 21) The method of claim 21, wherein the connective tissue comprises a ligament. ### Claim 24 (depends on 13) The method of claim 13, wherein the at least one sheet has a biomechanical strength that is equal to that of the elongate element. ### Claim 25 (depends on 13) The method of claim 13, wherein the at least one sheet has a stretchability that is equal to that of the elongate element.