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US 10,473,664 B2Granted
Heat-treated limulus amebocyte lysates
AssigneeCharles River Laboratories, Inc.
InventorMasakazu Tsuchiya
Life of this patent
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Abstract
The application provides heat-treated Limulus amebocyte lysates useful for detecting β-glucans.
Claims10
A method of detecting (1→3)-β-D-glucan in a sample, the method comprising:
- combining the sample with a heat-treated Limulus amebocyte lysate comprising (1→3)-β-D-glucan-sensitive Limulus Factor G and having an endotoxin reactivity less than 0.1% of the endotoxin reactivity of an untreated Limulus amebocyte lysate and detecting a change in an optical property of the sample.
Dependencies are inferred from the claim text.