Materials and methods for detecting cancer based on urinary levels of RHAMM

A kit for assaying RHAMM level and CA125 level, the kit consisting essentially of:

• a test apparatus and optionally, one or more controls, reagents for assaying RHAMM level and CA125 level, and one or more sample receivers,
• wherein the test apparatus is:
• i) an ELISA
• plate consisting of a well coated with a layer consisting of:
• an antibody against RHAMM or an antigen binding fragment of antibody against RHAMM and an antibody against CA125 or an antigen binding fragment of antibody against CA125;
• ii) an ELISA
• plate consisting of a first well coated with a layer consisting of an antibody against RHAMM or an antigen binding fragment of antibody against RHAMM and a second well coated with a layer consisting of an antibody against CA125 or an antigen binding fragment of antibody against CA125;
• iii) a point of care diagnostic device consisting of a test surface coated with a layer consisting of an antibody against RHAMM or an antigen binding fragment of antibody against RHAMM and an antibody or an antigen binding fragment of antibody against CA125;
• or
• iv) a point of care diagnostic device consisting of a test surface consisting of a first test surface and a second test surface, the first test surface coated with a layer consisting of an antibody against RHAMM or an antigen binding fragment of antibody against RHAMM and the second test surface coated with a layer consisting of an antibody against RHAMM or an antigen binding fragment of antibody against CA125.