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US 10,472,653 B2Granted
Recombinant host cells for the production of malonate
AssigneeLygos, Inc.
InventorsJeffrey A. Dietrich, Jeffrey L. Fortman, Eric J. Steen
Life of this patent
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Abstract
Systems and methods for the production of malonate in recombinant host cells.
Claims5
A recombinant Escherichia coli cell comprising the heterologous malonyl-CoA hydrolase of SEQ ID:
- 50, wherein X1 is N.
A recombinant Escherichia coli cell comprising a heterologous malonyl-CoA hydrolase, wherein said heterologous malonyl-CoA hydrolase an enzyme with an amino sequence that has at least 75% identity to consensus sequence SEQ ID NO:9 and is identical to SEQ ID NO:9 at positions corresponding to G67, G68, G120, E143, and D151;
- and wherein X1 is N.
Dependencies are inferred from the claim text.