SGC stimulators
AssigneeCyclerion Therapeutics, Inc.
InventorsGlen Robert Rennie, Rajesh R. Iyengar, Thomas Wai-Ho Lee, Paul Allan Renhowe, Joon Jung
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Abstract
The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutical formulations comprising them and their uses thereof, alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP), or both, or an upregulation of the NO pathway is desirable. The compounds are of Formula I:
Claims2
A compound of Formula I-1, or a pharmaceutically acceptable salt thereof,
Dependencies are inferred from the claim text.