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US 10,471,279 B2Granted
Proton dose imaging method and apparatus
AssigneeThe Trustees of the University of Pennsylvania
InventorsRobert Hollebeek, Derek Dolney
Life of this patent
Estimating the term…
Abstract
Particle therapy systems and methods for particle dose imaging are provided. A particle therapy system includes a particle beam source for generating a particle beam; and at least one particle detector including an ionization chamber having a mesh electrode. The at least one particle detector is configured to receive the particle beam and to generate an ionization current responsive to the received particle beam. The ionization current may be used to characterize the particle beam.
Claims20
A particle therapy system comprising:
- a particle therapy beam source for generating a particle therapy beam the particle therapy beam including particles selected from the group consisting of protons and positive ions;
- a plurality of particle detectors at least partially overlapping one another in a stacked configuration and configured to detect the particle therapy beam, each particle detector including an ionization chamber configured to receive a gas, a mesh electrode, at least one anode, and an amplification gap between the mesh electrode and the at least one anode, wherein one or more of a size of the amplification gap, a composition of the gas, or a gain of one or more of the plurality of particle detectors enables a linear response of the one or more particle detectors for a 2 Gray dose to a one liter volume delivered by the particle therapy beam within about two minutes or less;
- and
- an analyzer configured to generate a three-dimensional representation of the particle therapy beam based on the detection of the particle therapy beam by at least a portion of the plurality of particle detectors in the stacked configuration.
1 more element
A method for particle dose imaging, the method comprising:
- generating a particle therapy beam, the particle therapy beam including particles selected from the group consisting of protons and positive ions;
- directing the particle therapy beam to be incident on a plurality of particle detectors at least partially overlapping one another in a stacked configuration such that the plurality of particle detectors detect the particle therapy beam, each particle detector including an ionization chamber configured to receive a gas, a mesh electrode, at least one anode, and an amplification gap between the mesh electrode and the at least one anode, wherein one or more of a size of the amplification gap, a composition of the gas, or a gain of one or more of the plurality of particle detectors enables a linear response of the one or more particle detectors for a 2 Gray dose to a one liter volume delivered by the particle therapy beam within about two minutes or less;
- and
- generating a three-dimensional representation of a particle dose of the particle therapy beam based on detection of the particle therapy beam by at least a portion of the plurality of particle detectors in the stacked configuration.
1 more element
A particle therapy system comprising:
- a particle therapy beam source for generating a particle therapy beam, the particle therapy beam including particles selected from the group consisting of protons and positive ions;
- and
- a plurality of particle detectors at least partially overlapping one another in a stacked configuration wherein each of the particle detectors comprise an ionization chamber configured to receive a gas, a mesh electrode, at least one anode, and an amplification gap between the mesh and the at least one anode, wherein one or more of a size of the amplification gap, a composition of the gas, or a gain of one or more the plurality particle detector enables the plurality of particle detectors to generate one or more signals for representing a three-dimensional dose distribution of the particle therapy beam for a 2 Gray dose to a one liter volume delivered by the particle therapy beam within about two minutes or less.
A method for particle dose imaging, the method comprising:
- generating a particle therapy beam adapted, the particle therapy beam including particles selected from the group consisting of protons and positive ions;
- and
- directing the particle therapy beam to be incident on at least one particle detector of a plurality of particle detectors at least partially overlapping one another in a stacked configuration, wherein each of the particle detectors comprise an ionization chamber comprising a gas, a mesh electrode, at least one anode, and an amplification gap between the mesh and the at least one anode, wherein one or more of a size of the amplification gap, a composition of the gas, or a gain of one or more the plurality particle detector enables the plurality of particle detectors to generate one or more signals for representing a three-dimensional dose distribution of the particle therapy beam for a 2 Gray dose to a one liter volume delivered by the particle therapy beam within about two minutes or less.
Dependencies are inferred from the claim text.