Silicone free drug delivery devices
AssigneeW. L. Gore & Associates, Inc.
InventorsEdgar G. Ashmead, Edward C. Gunzel, Michael P. Moritz
Life of this patent
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Abstract
A pre-filled syringe having containing therein at least one therapeutic is provided. The syringe contains a silicone free barrel and an elastomeric syringe stopper that is covered with an expanded polytetrafluoroethylene barrier layer. The presence of a barrier layer that is at least partially porous on the outside of the syringe stopper improves the seal between the stopper and syringe barrel and minimizes the sliding force. In some embodiments, the barrel is formed of a glass material such as a borosilicate glass, that is free of silicone or other lubricants.
Claims19
A pre-filled syringe comprising:
- a silicone free syringe barrel containing at least one therapeutic;
- and
- a syringe stopper comprising:
- (a) an elastomeric material,
- (b) a composite layer having a first side consisting of an expanded polytetrafluoroethylene film and a second side comprising a thermoplastic fluoropolymer, and
- (c) a densified expanded polytetrafluoroethylene film where the composite layer is adjacent to the elastomeric material and the densified expanded fluoropolymer film is adjacent to the second side of the composite layer.
A pre-filled syringe comprising:
- a silicone free syringe barrel containing at least one therapeutic;
- and
- an elastomeric stopper comprising:
- an elastomeric material;
- a composite layer having a first side consisting of an expanded polytetrafluoroethylene film and a second side comprising a thermoplastic fluoropolymer;
- and
- a fluoropolymer film,
- wherein the first side of the composite layer is bonded to the elastomeric material and the second side is bonded to the fluoropolymer film.
Dependencies are inferred from the claim text.