Medical delivery device with laminated stopper
AssigneeW. L. Gore & Associates, Inc.
InventorsGreg Rusch, Robert C. Basham
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to a medical delivery device that includes a barrel having an inner surface, a plunger rod having a distal end inserted within the barrel, and a stopper attached to the distal end of the plunger rod and contacting at least a portion of the inner surface of the barrel. In at least one embodiment, the inner surface is hydrophilic. The stopper may include an elastomeric body, one or more fluoropolymer layers, and two or more ribs laminated with the one or more fluoropolymer layers. In some embodiments, the contact width between at least one rib having a sealing surface and the portion of the inner surface of the barrel measured at a compressibility of greater than about 7.9% of the stopper is less than about 1.0 mm.
Claims27
A medical delivery device comprising:
- a barrel having an inner surface;
- a plunger rod having a distal end inserted within the barrel;
- a stopper attached to the distal end of the plunger rod and contacting at least a portion of the inner surface of the barrel, the stopper comprising an elastomeric body, one or more fluoropolymer layers, and two or more ribs having a sealing surface and being positioned on the one or more fluoropolymer layers;
- wherein a contact width between at least one of said two or more ribs and a portion of the inner surface of the barrel measured at a compressibility of greater than about 7.9% of the stopper is less than about 1.0 mm.
A plunger rod comprising:
- a distal end that is insertable in a barrel having an inner surface;
- and
- a stopper attached to the distal end and configured to contact at least a portion of the inner surface of the barrel, the stopper comprising an elastomeric body, one or more fluoropolymer layers, and two or more ribs positioned on the one or more fluoropolymer layers,
- wherein each rib of said two or more ribs having a sealing surface comprises a radius of curvature at an apex of each respective rib that is less than about 0.22 mm, a ratio of a maximum outer diameter of all said ribs having a sealing surface to an inner diameter of the inner surface of the barrel is greater than about 1.08, and
- wherein the plunger rod is configured such that when the plunger rod is inserted in the barrel having an inner diameter of an inner surface of the barrel, a contact width between at least one of said two or more ribs having a sealing surface and the portion of the inner surface of the barrel measured at a compressibility of greater than 7.9% of the stopper is less than about 1.0 mm.
A stopper insertable in a barrel having an inner surface, the stopper comprising:
- an elastomeric body;
- one or more fluoropolymer layers;
- and
- two or more ribs,
- wherein at least one of the two or more ribs is positioned on the one or more fluoropolymer layers and is configured to contact at least a portion of the inner surface of the barrel;
- and
- wherein each rib of said two or more ribs comprises a radius of curvature at an apex of each respective rib that is less than about 0.22 mm, a ratio of a maximum outer diameter of all said ribs to an inner diameter of the inner surface of the barrel is greater than about 1.08, and
- wherein the stopper is configured such that when the stopper is inserted in the barrel, a contact width between at least one of said two or more ribs and the portion of the inner surface of the barrel measured at a compressibility of greater than 7.9% of the stopper is less than about 1.0 mm.
Dependencies are inferred from the claim text.