Pharmaceutical composition for injection
AssigneeSumitomo Dainippon Pharma Co., Ltd.
InventorsSatoshi Tanaka, Tomomi Nakatani
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Abstract
The present invention provides an injectable pharmaceutical composition containing the following components: (a) one or more kinds of peptides selected from a peptide represented by the formula (1): wherein the bond between Cys and Cys is a disulfide bond, Leu-OH shows that the C-terminal of Leu is a free carboxyl group, and other bond is a peptide bond, a peptide consisting of the amino acid sequence shown by Trp-Ala-Pro-Val-Leu-Asp-Phe-Ala-Pro-Pro-Gly-Ala-Ser-Ala-Tyr-Gly-Ser-Leu (SEQ ID NO: 1) and salts thereof, (b) trehalose or trehalose hydrate, and (c) a pH adjuster.
Claims22
An injectable pharmaceutical composition comprising the following components:
- (a) one or more kinds of peptides selected from the group consisting of:
- (i) the peptide represented by the formula (1):
- wherein the bond between Cys and Cys is a disulfide bond, Leu-OH shows that the C-terminal of Leu is a free carboxyl group, and other amino acids in formula (I) are linked by peptide bonds,
- (ii) the peptide consisting of the amino acid sequence shown by Trp-Ala-Pro-Val-Leu-Asp-Phe-Ala-Pro-Pro-Gly-Ala-Ser-Ala-Tyr-Gly-Ser-Leu (SEQ ID NO:
- 1) and
- (iii) salts thereof,
- (b) trehalose or trehalose hydrate, and
- (c) a pH adjuster.
Dependencies are inferred from the claim text.