Microparticles
AssigneeSpheritech Ltd
InventorDonald A. Wellings
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Abstract
The invention provides a blood substitute product comprising haemoglobin and a self-assembled microparticle having an acid having two or more acid groups and an organic base in a solvent. The particle is of micron scale. The microparticle may be obtained by contacting a bis-acid and organic base in a hydrophilic solvent, wherein the acid is insoluble or sparingly soluble in the hydrophilic solvent and the organic base is soluble in a hydrophilic solvent.
Claims7
A blood substitute product comprising mammalian haemoglobin and a self-assembled microparticle in which the microparticle comprises an acid having two or more acid groups and an organic base which is soluble in a hydrophilic solvent;
- wherein the acid comprises brassylic acid, sebacic acid, and/or azelaic acid;
- wherein the organic base comprises one or more of N-methylmorpholine, N,N-dimethylaminoethanol, 4-dimethylaminopyridine, imidazole, 1-methylamidazole, poly(diallyldimethylammonium chloride) (PDAC), didecyldimethylammonium chloride (DDAC), dodecyldipropylenetriamine (DDPT) and poly epsilon lysine.
Dependencies are inferred from the claim text.