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US 10,471,118 B2Granted
Retinylamine derivitives for treatment of ocular disorders
AssigneeCase Western Reserve University
InventorsKrzysztof Palczewski, Zheng-Rong Lu
Life of this patent
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Abstract
A pharmaceutical composition includes a retinylamine derivative having the following formula (I): where R1 is an amino acid residue, a dipeptide or a tripeptide that is linked to the retinylamine by an amide bond.
Claims6
A method of treating an ocular disorder in a subject in need thereof, the method comprising:
- administering to the subject a pharmaceutical composition comprising:
- a retinylamine derivative having the following formula:
- where R1 is an amino acid residue, or a dipeptide that is linked to the retinylamine by an amide bond, wherein R1 is selected from the group consisting of glycine, L-valine-glycine, and glycine-L-valine, wherein the ocular disorder is light-induced retinal degeneration.
Dependencies are inferred from the claim text.