Suspension of graphene oxide nanoflakes in water, its use and a method of preparation thereof
AssigneesSzkola Glowna Gospodarstwa Wiejskiego, Instytut Technologii Materialow Elektronicznych
InventorsEwa Sawosz Chwalibog, Marta Kutwin, Slawomir Jaworski, Mateusz Wierzbicki, Marta Grodzik, Anna Hotowy, Ludwika Lipinska, Joanna Jagiello
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Abstract
The present invention relates to a water suspension of graphene oxide nanoflakes decorated by nanoparticles of metallic platinum, characterised in that it comprises: • 100 μg/ml to 500 μg/ml of graphene oxide nanoflakes, • 5 μg/ml to 50 μg/ml of nanoparticles of metallic platinum (Pt°), deposited on the surface of graphene oxide nanoflakes. The invention also relates to a method of preparing such suspension and its use as an antitumor agent.
Claims1
A method of treating human or animal tumors, the method comprising:
- depositing nanoparticles of aqueous colloidal metallic platinum in zero oxidation state on a surface of graphene oxide nanoflakes and forming a water suspension by using ultrasonic energy in an ultrasound bath thereof, wherein graphene oxide nanoflakes are present in the water suspension in a range of about 100 μg/ml to about 500 μg/ml and nanoparticles of metallic platinum are present in the suspension in a range of about 5 μg/ml to about 50 μg/ml, wherein platinum nanoparticles and graphene oxide nanoflakes are bound together through electronic interactions and graphene oxide nanoflakes and platinum nanoparticles are non-reduced in the water suspension, administering the water suspension of non-reduced graphene oxide nanoflakes and nanoparticles of metallic platinum to human or animal tumors by direct injection of the water suspension into the tumor or area directly surrounding the tumor, wherein the water suspension functions as an antitumor agent.
Dependencies are inferred from the claim text.