Methods for decreasing the incidence of necrotizing enterocolitis in infants, toddlers, or children using human milk oligosaccharides

A method of improving the feeding tolerance of an infant, toddler, or child, the method comprising administering to an infant, toddler, or child in need thereof a nutritional composition comprising 2′-fucosyllactose and 6′-sialyllactose, wherein the 2′-fucosyllactose and 6′-sialyllactose are present in a total amount of from about 0.001 mg/mL to about 20 mg/mL.

A shelf stable synthetic formula for improving the feeding tolerance of an infant, toddler, or child, the synthetic formula comprising from about 0.001 mg/mL to about 20 mg/mL of an oligosaccharide blend, wherein the oligosaccharide blend comprises a first oligosaccharide, 2′-fucosyllactose, in a concentration of from 0.001 mg/mL to less than 2.0 mg/mL, and a second oligosaccharide, 6′-sialyllactose, in a concentration of from 0.001 mg/mL to less than 0.25 mg/mL.