Treprostinil derivatives and compositions and uses thereof
AssigneeCorsair Pharma, Inc.
InventorsXiaoming Zhang, Meenakshi S. Venkatraman, Cyrus K. Becker
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Abstract
The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Claims16
A pharmaceutical composition comprising one or more pharmaceutically acceptable excipients or carriers and a compound selected from the group consisting of:
- or a pharmaceutically acceptable salt, solvate, hydrate, clathrate, polymorph or stereoisomer thereof.
A method of treating a medical condition responsive to treatment with treprostinil, comprising administering to a subject in need of treatment a therapeutically effective amount of a compound selected from the group consisting of:
- or a pharmaceutically acceptable salt, solvate, hydrate, clathrate, polymorph or stereoisomer thereof.
Dependencies are inferred from the claim text.