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US 10,457,942 B2Granted
Exosomes and micro-ribonucleic acids for tissue regeneration
AssigneeCedars-Sinai Medical Center
InventorsEduardo Marbán, Ke Cheng, Ahmed Ibrahim
Life of this patent
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Abstract
Several embodiments relate to methods of repairing and/or regenerating damaged or diseased tissue comprising administering to the damaged or diseased tissues compositions comprising exosomes. In several embodiments, the exosomes comprise one or more microRNA that result in alterations in gene or protein expression, which in turn result in improved cell or tissue viability and/or function.
Claims11
A method for producing a therapeutic composition comprising:
- harvesting a population of exosomes from cardiospheres or cardiosphere-derived cells (CDCs) wherein said exosomes comprise microRNAs mir-210 and miR-146a.
A method of producing a therapeutic composition comprising:
- harvesting a population of exosomes from cardiosphere-derived cells (CDCs).
Dependencies are inferred from the claim text.