Biological sample collection, storage, and transport system and method

A method for biological sample collection comprising:

• identifying a collection site;
• providing a collection device comprising:
• a sheath and a collection assembly slideably coupled to the sheath, the collection assembly comprising a support shaft, a swab coupled to a distal support shaft end, a handle coupled to a proximal support shaft end, the handle comprising a top surface and a bottom surface;
• a base coupled to a sheath proximal end, the base comprising a stop channel;
• configuring the collection device in a first position, such that the swab head is completely disposed within the sheath and the handle extends proximally from the base;
• moving a distal sheath end close to the collection site;
• and
• configuring the sample collection device into a second position by applying pressure to the handle, such that the swab head fully extends through a proximal opening in the sheath, and the handle is disposed within the stop channel such that a radially outward facing handle surface contacts and frictionally couples to a radially inward facing stop channel surface with sufficient force to prevent the handle from rotating when the collection assembly is in the extended position and the swab head is rotated while contacting the collection site;
• applying the swab head to the collection site to collect a biological sample;
• configuring the collection assembly into the first position;
• and
• attaching a seal over the distal sheath end to enclose the swab head and the biological sample.