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US 10,442,751 B2Granted
Method for preparing substituted alkyl cycloalkanones
AssigneeSymrise AG
InventorsAtia Hanan, Reinhard Eckelt, Angela Koeckritz, Johannes Panten, Peter Esser, Oskar Koch
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Abstract
The present invention relates to a method for producing a substituted alkyl cycloalkanone, comprising the alkylation of a cycloalkanone with an alkene derivative in the presence of a metal oxide, where n is 2 to 20, m is 0 to 10, and R is a functional group.
Claims13
A method for preparing a substituted alkyl cycloalkanone of formula I
- comprising the alkylation of a cycloalkanone of formula II
- with an alkene derivative of formula III
- in the presence of a metal oxide, where n is 2 to 20, m is 0 to 10 and R is a hydroxyl, carboxyl, carbonyloxyalkyl, formyloxy, alkylcarbonyloxy, arylcarbonyloxy or benzylcarbonyloxyalkyl group or is one of the following groups:
- wherein R′ is an alkyl, aryl, heteroaryl, alkylaryl or cycloalkyl radical;
- and
- wherein the metal oxide is a copper oxide, iron oxide, manganese oxide, indium oxide, cobalt oxide, or a mixture thereof.
3 more elements
Dependencies are inferred from the claim text.