Method for manufacturing a dispensing device for eye drops
AssigneeDompé Farmaceutici S.P.A.
InventorMarco Maria Gentile
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Abstract
A process for the production of a device for dispensing eye drops. The process includes the steps of providing a first container and a second container configured to be engaged in a fluid-tight manner, providing a spacer, introducing a water-based solution inside the first container, introducing a solution or dispersion comprising a drug inside the second container, arranging the spacer between the first and second containers, engaging in a fluid-tight manner the second container and the first container, and freeze-drying the solution or dispersion comprising the drug.
Claims14
Process for production of a device for dispensing eye drops, comprising steps of:
- providing a first container comprising a tubular element with an open end portion;
- providing a second container comprising a wall engageable in a fluid-tight manner around the tubular element;
- providing a spacer having oppositely arranged bases which are substantially parallel;
- introducing water or a water-based solution for injection inside the first container;
- introducing a solution or a dispersion comprising a drug of one or more of a chemical and biotechnological nature inside the second container;
- arranging the spacer between the first and second containers so that the bases are in contact with the first and second containers;
- engaging in a fluid-tight manner the wall of the second container around the tubular element of the first container;
- and
- freeze-drying the solution or the dispersion comprising the drug;
- wherein the step of freeze-drying the solution or the dispersion comprising the drug is performed following assembly of the first and second containers with the spacer and comprises subjecting the assembly of the first container and the second container and the spacer to a freeze-drying atmosphere.
Dependencies are inferred from the claim text.