# US 10,441,814 B2 · Method and apparatus to employ a multi-layer multi-leaf collimator when administering a radiation therapy treatment

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- Number: US 10,441,814 B2
- Document ID: US10441814B2
- Status: Granted
- Kind: B2
- Application number: 14/865,890
- Filed: 2015-09-25
- Published: 2017-03-30
- Granted: 2019-10-15
- Earliest claimed: 2015-09-25
- Assignees: Varian Medical Systems International AG
- Applicants: Varian Medical Systems, Inc.; Varian Medical Systems International AG
- Inventors: Janne I. Nord; Jarkko Y. Peltola; Esa Kuusela; Steven W. Prince
- Web page: https://patentgrep.com/patent/US10441814B2

## CPC

- A61N 5/1045: {using a multi-leaf collimator, e.g. for intensity modulated radiation therapy or IMRT}
- A61N 5/1036: {Leaf sequencing algorithms}
- G21K 1/046: {varying the contour of the field, e.g. multileaf collimators}
- A61N 2005/1074: {Details of the control system, e.g. user interfaces}
- A61N 2005/1095: {Elements inserted into the radiation path within the system, e.g. filters or wedges}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- G21K: HANDLING OF PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES

## Abstract

A control circuit administers a radiation treatment plan that specifies a planned total radiation dose for a radiation treatment session for a given patient by modulating a radiation beam with at least one high-resolution aperture that is formed using one of a plurality of linearly-sequential high-resolution aperture possibilities. By one approach the foregoing comprises modulating the radiation beam using at least substantially only high-resolution apertures that are formed using a plurality of the linearly-sequential high-resolution aperture possibilities. In some cases the foregoing can comprise administering the radiation treatment plan using at least two separate radiation exposures for only a single treatment field, in which case, by one approach, each of the separate radiation exposures for the single treatment field can comprise modulating the radiation beam using at least substantially only high-resolution apertures.

## Claims

### Claim 1

A method for use with a radiation therapy treatment platform having a multi-layer multi-leaf collimation system wherein a proximal layer of a plurality of collimation leaf pairs are vertically offset with respect to a distal layer of a plurality of collimation leaf pairs such that the two multi-layer multi-leaf collimators combine to form a plurality of linearly-sequential high-resolution aperture possibilities, the method comprising:
by a control circuit:
administering a radiation treatment plan that specifies a planned total radiation dose for a radiation treatment session for a given patient by, at least in part and for a first treatment field, administering two and only two radiation exposures, wherein:
a first radiation exposure for the first treatment field comprises modulating a radiation beam using a first fixed aperture that includes at least one high-resolution aperture that is formed using one of the plurality of linearly-sequential high-resolution aperture possibilities; and
a second separate radiation exposure for the first treatment field comprises modulating the radiation beam using a second fixed aperture that is different from the first fixed aperture and that includes at least one high-resolution aperture that is formed using one of the plurality of linearly-sequential high-resolution aperture possibilities.

### Claim 2 (depends on 1)

The method of claim 1 wherein at least some of the plurality of linearly-sequential high-resolution aperture possibilities have a height resolution that is twice the resolution of aperture possibilities that are available with either of the proximal or distal layer of the plurality of collimation leaf pairs alone.

### Claim 3 (depends on 2)

The method of claim 2 wherein at least substantially all of the plurality of linearly-sequential high-resolution aperture possibilities have a height resolution that is twice the resolution of aperture possibilities that are available with either of the proximal or distal layer of the plurality of collimation leaf pairs alone.

### Claim 4 (depends on 1)

The method of claim 1 wherein at least one of the high-resolution apertures has at least one boundary defined only by the proximal layer and at least one other boundary defined only by the distal layer.

### Claim 5 (depends on 1)

The method of claim 1 wherein the first radiation exposure for the first treatment field comprises modulating a radiation beam using a first fixed aperture comprised of at least substantially only high-resolution apertures that are formed using the plurality of linearly-sequential high-resolution aperture possibilities and wherein the second radiation exposure for the first treatment field comprises modulating a radiation beam using a second fixed aperture that is different from the first fixed aperture and that is comprised of at least substantially only high-resolution apertures that are formed using the plurality of linearly-sequential high-resolution aperture possibilities.

### Claim 6 (depends on 1)

The method of claim 1 wherein the high-resolution apertures are grouped in sequential pairs and the sequential pairs of high-resolution apertures are separated from one another by a pair of sequential unused high-resolution aperture possibilities of the plurality of linearly-sequential high-resolution aperture possibilities.

### Claim 7

An apparatus comprising:
a source of therapeutic radiation configured to emit a radiation beam;
a multi-layer multi-leaf collimation system wherein a proximal layer of a plurality of collimation leaf pairs are vertically offset with respect to a distal layer of a plurality of collimation leaf pairs such that the two multi-layer multi-leaf collimators combine to form a plurality of linearly-sequential high-resolution aperture possibilities; and
a control circuit operably coupled to the source of therapeutic radiation and to the multi-layer multi-leaf collimation system, the control circuit being configured to administer a radiation treatment plan that specifies a planned total radiation dose for a radiation treatment session for a given patient, at least in part and for a first treatment field, by administering two and only two radiation exposures, wherein:
a first radiation exposure for the first treatment field comprises modulating a radiation beam using a first fixed aperture that includes at least one high-resolution aperture that is formed using one of the plurality of linearly-sequential high-resolution aperture possibilities; and
a second separate radiation exposure for the first treatment field comprises modulating the radiation beam using a second fixed aperture that is different from the first fixed aperture and that includes at least one high-resolution aperture that is formed using one of the plurality of linearly-sequential high-resolution aperture possibilities.

### Claim 8 (depends on 7)

The apparatus of claim 7 wherein at least some of the plurality of linearly-sequential high-resolution aperture possibilities have a height resolution that is twice the resolution of aperture possibilities that are available with either of the proximal or distal layer of the plurality of collimation leaf pairs alone.

### Claim 9 (depends on 8)

The apparatus of claim 8 wherein at least substantially all of the plurality of linearly-sequential high-resolution aperture possibilities have a height resolution that is twice the resolution of aperture possibilities that are available with either of the proximal or distal layer of the plurality of collimation leaf pairs alone.

### Claim 10 (depends on 7)

The apparatus of claim 7 wherein at least one of the high-resolution apertures has at least one boundary defined only by the proximal layer and at least one other boundary defined only by the distal layer.

### Claim 11 (depends on 7)

The apparatus of claim 7 wherein the control circuit is configured to administer the radiation treatment plan by modulating the radiation beam using at least substantially only high-resolution apertures that are formed using the plurality of the linearly-sequential high-resolution aperture possibilities.

### Claim 12 (depends on 7)

The apparatus of claim 7 wherein the high-resolution apertures are grouped in sequential pairs and the sequential pairs of high-resolution apertures are separated from one another by a pair of sequential unused high-resolution aperture possibilities of the plurality of linearly-sequential high-resolution aperture possibilities.

### Claim 13

A method for use with a radiation therapy treatment platform having a multi-layer multi-leaf collimation system wherein a proximal layer of a plurality of collimation leaf pairs are vertically offset with respect to a distal layer of a plurality of collimation leaf pairs such that the two multi-layer multi-leaf collimators combine to form a plurality of linearly-sequential high-resolution aperture possibilities, the method comprising:
by a control circuit:
administering a radiation treatment plan that specifies a planned total radiation dose for a radiation treatment session for a given patient by, at least in part and for a first treatment field, administering two radiation exposures, wherein:
a first radiation exposure for the first treatment field comprises modulating a radiation beam using a first fixed aperture that includes at least one high-resolution aperture that is formed using one of the plurality of linearly-sequential high-resolution aperture possibilities; and
a second separate radiation exposure for the first treatment field comprises modulating the radiation beam using a second fixed aperture that is different from the first fixed aperture and that includes at least one high-resolution aperture that is formed using one of the plurality of linearly-sequential high-resolution aperture possibilities.
