# US 10,441,778 B2 · Optical stimulation implant

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- Number: US 10,441,778 B2
- Document ID: US10441778B2
- Status: Granted
- Kind: B2
- Application number: 15/470,767
- Filed: 2017-03-27
- Published: 2017-10-05
- Granted: 2019-10-15
- Earliest claimed: 2016-03-29
- Assignees: Boston Scientific Neuromodulation Corporation
- Applicants: Boston Scientific Neuromodulation Corporation
- Inventors: William G. Orinski
- Web page: https://patentgrep.com/patent/US10441778B2

## CPC

- A61N 1/0534: {Electrodes for deep brain stimulation}
- A61B 5/686: {Permanently implanted devices, e.g. pacemakers, other stimulators, biochips (A61B5/6861 takes precedence)}
- A61N 1/0536: {Preventing neurodegenerative response or inflammatory reaction}
- A61N 1/0539: {Anchoring of brain electrode systems, e.g. within burr hole}
- A61N 1/3605: {Implantable neurostimulators for stimulating central or peripheral nerve system}
- A61N 1/36082: {Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease}
- A61N 1/37211: {Means for communicating with stimulators}
- A61N 1/0526: {Head electrodes (A61N1/0551 takes precedence)}
- A61N 1/0529: {Electrodes for brain stimulation}
- A61N 5/0622: {Optical stimulation for exciting neural tissue}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

An implantable medical device for providing phototherapy to a patient's brain is disclosed. The device includes a housing containing a light source for providing phototherapy to a patient. A light path is attached to the housing. The implantable medical device is configured to be positioned between a patient's skull and scalp with the light path extending into the patient's brain, such that light from the light source can irradiate a target position within the patient's brain. The implantable medical device is powered and controlled by an implantable pulse generator (IPG) that may be implanted into a patient's tissue remotely from the device and connected to the device by wire leads.

## Claims

### Claim 1

A medical device, comprising:
a housing configured to be mounted between a patient's skull and scalp and to receive electrical power via one or more electrical leads from an implantable pulse generator (IPG) implanted in the patient remote from the patient's head;
a light source contained within the housing configured to be powered by the electrical power received from the IPG; and
a light path attached to and extending from the housing and configured to provide a path for light from the light source to a target neural area, wherein the light path comprises:
a proximal section configured to traverse a portion of the patient's skull between the skull and scalp,
an arcuate section configured to penetrate through a hole in the skull, and
a light pipe configured to penetrate the brain to the target neural area, the light pipe comprising a hollow tubular member having a first end and a second end, wherein the second end comprises a diffuser or lens attached to the hollow tubular member, wherein,
a first end of the proximal section connects to the housing and a second end of the proximal section connects to a first end of the arcuate section, and wherein
a second end of the arcuate section connects to the first end of the light pipe, and
a fiber optic member contained within the proximal section and the arcuate section and terminating in the arcuate section so that the fiber optic member does not extend through the tubular member of the light pipe and configured to allow light from the fiber optic member to traverse the interior of the hollow tubular member to the diffuser or lens.

### Claim 2 (depends on 1)

The medical device of claim 1, wherein the housing comprises a hermetically sealed inner portion overmolded in an overmolding material.

### Claim 3 (depends on 2)

The medical device of claim 2, wherein the overmolding material is a silicone.

### Claim 4 (depends on 2)

The medical device of claim 2, further comprising one or more feedthroughs providing electrical communication for the one or more electrical leads into and out of the hermetically sealed inner portion.

### Claim 5 (depends on 2)

The medical device of claim 2, wherein the hermetically sealed inner portion contains a printed circuit board (PCB) electrically connected to the light source.

### Claim 6 (depends on 5)

The medical device of claim 5, further comprising a temperature sensor electrically connected to the PCB.

### Claim 7 (depends on 1)

The medical device of claim 1, wherein the light pipe second end contains the diffuser.

### Claim 8 (depends on 1)

The medial device of claim 1, wherein the light pipe is configured to connect to and disconnect from the arcuate section.

### Claim 9 (depends on 8)

The medical device of claim 8, wherein the light pipe is configured to connect to and disconnect from the arcuate section by screwing or snapping to/from the arcuate section.

### Claim 10 (depends on 1)

The medical device of claim 1, wherein the light pipe further comprises at least one electrode configured to provide electrical neuromodulation.

### Claim 11 (depends on 10)

The medical device of claim 10, wherein the at least one electrode comprises a ring electrode integrated with the light pipe.
