# US 10,441,744 B2 · Flushable catheter affixed to a wash line activated by a microfluidic pressure switch > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 10,441,744 B2 - Document ID: US10441744B2 - Status: Granted - Kind: B2 - Application number: 14/760,792 - Filed: 2014-05-12 - Published: 2015-12-03 - Granted: 2019-10-15 - Earliest claimed: 2013-05-13 - Applicants: Yannan Ouyang - Inventors: Yannan Ouyang - Web page: https://patentgrep.com/patent/US10441744B2 ## CPC - A61M 25/00: Catheters; Hollow probes (dilators A61M29/00; {peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00} ; for measuring or testing A61B; {materials for catheters A61L29/00}) - A61M 25/0017: {specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections} - A61M 25/003: {characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves (catheter tips A61M25/0067)} - A61M 39/22: Valves or arrangement of valves {(A61M39/02, A61M39/0247, A61M39/16 take precedence; regulating valves in infusion systems A61M5/16881; in devices worn by the patient for the reception of urine, faeces, catamenial or other discharge, or in colostomy devices A61F5/4405)} - A61M 39/24: Check- or non-return valves - C11D 3/386: Preparations containing enzymes {, e.g. protease or amylase} - C11D 3/48: Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions - A61L 2/18: Liquid substances - A61L 2103/15: Laboratory, medical or dentistry appliances, e.g. catheters or sharps - A61L 2202/14: Means for controlling sterilisation processes, data processing, presentation and storage means, e.g. sensors, controllers, programs - A61M 2025/0019: {Cleaning catheters or the like, e.g. for reuse of the device, for avoiding replacement} - A61M 2025/0031: {characterized by lumina for withdrawing or delivering, i.e. used for extracorporeal circuit treatment} - C11D 2111/14: Hard surfaces - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - C11D: DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) ## Abstract This invention relates to systems for delivering medical devices, as well as related systems and methods. The invention also relates to methods of prevention and treatment of biofilm related contamination of systems or devices for medication delivery and methods of treating medical devices, such as catheters, to prevent infection from said device. ## Claims ### Claim 1 An implantable medical device including a catheter, wherein said catheter comprises: a distal end, a central line connected to said distal end, a flushing line, and a valve comprised of a microfluidic movable pressure switch, said microfluidic movable pressure switch configured to move between said distal end and said flushing line, wherein the valve is configured so that when the microfluidic movable pressure switch is engaged to said flushing line, fluid flows from said central line to said distal end and when said microfluidic movable switch is engaged to said distal end, fluid flows from said flushing line to said central line, wherein said valve is attached within an end of said flushing line and said valve engages said central line with an external bracing structure; said microfluidic movable pressure switch is attached to a central rod disposed within at least one internal bracing feature; said microfluidic movable pressure switch attached to said central rod, wherein a tip of said microfluidic movable pressure switch is configured to block a narrowed portion of said central line on a tip of said catheter to prevent fluid flow. ### Claim 2 (depends on 1) The device of claim 1, wherein said catheter comprises a central venous catheter. ### Claim 3 (depends on 1) The device of claim 1, wherein said catheter comprises a urinary catheter. ### Claim 4 A kit comprising: a plurality of cleaning reagents, said plurality of cleaning reagents comprising: a) digestive enzyme solution, b) calcium deficient buffer with high ion concentrations c) a solution comprising 70% ethanol, and d) physiological saline solution; a catheter comprised of: a distal end, a central line connected to said distal end, a flushing line, and a valve comprised of a microfluidic movable pressure switch, said microfluidic movable pressure switch is configured to move between said distal end and said flushing line, wherein said valve is configured so that when said microfluidic movable pressure switch is engaged to said flushing line, fluid flows from said central line to said distal end and when said microfluidic movable switch is engaged to said distal end, fluid flows from said flushing line to said central line wherein said valve is attached within an end of said flushing line and said valve engages said central line with an external bracing structure; said microfluidic movable pressure switch is attached to a central rod disposed within at least one internal bracing feature; said microfluidic movable pressure switch attached to said central rod, wherein a tip of said microfluidic movable pressure switch is configured to block a narrowed portion of said central line to prevent fluid flow. ### Claim 5 (depends on 4) The kit of claim 4, wherein said digestive enzyme solution contains trypsin. ### Claim 6 (depends on 4) The kit of claim 4, wherein said calcium deficient buffer with high ion concentration contains a chelating agent.