# US 10,441,718 B2 · Device for the prevention of overdose by opiate and depressant users

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- Number: US 10,441,718 B2
- Document ID: US10441718B2
- Status: Granted
- Kind: B2
- Application number: 15/054,111
- Filed: 2016-02-25
- Published: 2017-08-31
- Granted: 2019-10-15
- Earliest claimed: 2016-02-25
- Applicants: David Tchao
- Inventors: David Tchao; Paul Tchao
- Web page: https://patentgrep.com/patent/US10441718B2

## CPC

- A61M 5/1723: {using feedback of body parameters, e.g. blood sugar or pressure}
- A61B 5/0205: Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
- A61B 5/14532: {for measuring glucose, e.g. by tissue impedance measurement}
- A61B 5/14551: {for measuring blood gases}
- A61B 5/4839: {combined with drug delivery}
- A61B 5/746: {Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms}
- A61K 31/137: Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine {or methadone}
- A61K 31/167: having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
- A61K 31/46: 8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A61K 31/56: Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K 38/26: Glucagons
- A61K 38/28: Insulins
- A61M 5/14244: {adapted to be carried by the patient, e.g. portable on the body}
- A61M 15/085: {Fixing means therefor}
- A61B 5/021: Measuring pressure in heart or blood vessels
- A61B 5/02438: {with portable devices, e.g. worn by the patient}
- A61B 5/4845: {Toxicology, e.g. by detection of alcohol, drug or toxic products (A61B5/4848 takes precedence)}
- A61B 5/6819: {Nose}
- A61B 5/6824: {Arm or wrist}
- A61M 5/2053: {Media being expelled from injector by pressurised fluid or vacuum (for infusion A61M5/145, A61M5/155)}
- A61M 2202/049: Toxic
- A61M 2205/3592: using telemetric means, e.g. radio or optical transmission
- A61M 2205/50: with microprocessors or computers
- A61M 2205/8206: battery-operated
- A61M 2205/8225: using incorporated gas cartridges for the driving gas
- A61M 2230/06: Heartbeat rate only
- A61M 2230/30: Blood pressure (A61M2230/04 takes precedence)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)

## Abstract

An automated wearable device measure physiological signals, and when parameters which cause the wearer to be at risk are measured, the device delivers an antidote for a given medical condition. This prevents overdose or medical conditions from occurring.

## Claims

### Claim 1

A wearable medication delivery device comprising:
a housing;
a band connected to the housing for attaching the housing to a patient;
a compressed gas cylinder located inside the housing;
a piston chamber in fluid communication with the gas cylinder, the fluid path having a gas release valve;
a piston located in the piston chamber;
a medication-filled syrette operably connected to the piston;
a battery to power the device;
a vital sign sensor; and
a central processing unit configured to actuate the valve to release the gas, forcing the syrette into the skin, injecting the wearer with the medication, in response to a change in vital signs.

### Claim 2 (depends on 1)

The device of claim 1 further comprising a radio-emitter operably connected to the central processing unit wherein activation of the injection is coupled with radio emissions from the device which give real time medical information to incoming emergency medical professionals.

### Claim 3

A nasal spray device comprising:
a set of clips configured to spray an antidote into the sinuses;
a compressed gas cylinder containing the antidote;
a spray control valve connected between the cylinder and the clips;
a central processing unit attached to the cylinder having a breathing sensor and a radio emitter; and
wherein the processing unit is configured to activate the valve to release of the antidote as a nasal mist directly into the sinuses in response to the breathing sensor.

### Claim 4

A device for spraying an antidote toward a face comprising:
a face mask comprising a transparent face and upper and lower attachment rods for securing the mask to the head;
a compressed gas cylinder containing the antidote, the cylinder being attached to the mask;
a conduit connected between the cylinder and the inside of the mask to release a mist of opiate overdose antidote as a nasal mist into the mask;
a spray control valve connected between the cylinder and the conduit;
a central processing unit attached to the mask configured to receive information from sensors capable of detecting an overdose; and
a radio-emitter connected to the central processing unit, the emitter capable of emitting radio signals with medical information about the wearer when the sensors detect an overdose.

### Claim 5 (depends on 1)

The device of claim 1 further comprising:
a radio-emitter connected to the central processing unit;
wherein the vital sign sensor is a blood pressure sensor, a pulse rate sensor, or a pulse oximetry sensor; and
wherein when a predetermined change is detected in the vital sign sensor;
the valve is actuated; and
a radio-signal alarm is generated alerting emergency medical technicians.

### Claim 6 (depends on 1)

The device of claim 1 wherein the medication is epinephrine.

### Claim 7 (depends on 1)

The device of claim 1 wherein the medication is noxalone.

### Claim 8 (depends on 1)

The device of claim 1 wherein the medication is a steroid.

### Claim 9 (depends on 1)

The device of claim 1 wherein the medication is lidocaine and the vital sign sensor is a heartbeat sensor capable of detecting multiple irregular heartbeats.

### Claim 10 (depends on 1)

The device of claim 1 wherein the medication is a blood pressure lowering drug and the vital sign sensor is a blood pressure sensor capable of detecting when the blood pressure is dangerously high.

### Claim 11 (depends on 1)

The device of claim 1 wherein the medication is atropine the vital sign sensor is a heartbeat sensor capable of detecting when the pulse is too low.

### Claim 12 (depends on 1)

The device of claim 1 further comprising a membrane located between the syrette and a skin surface, the membrane being capable of penetration by the syrette.

### Claim 13 (depends on 1)

The device of claim 1 further comprising:
a radio-emitter operably connected to the central processing unit wherein activation of the injection is coupled with radio emissions from the radio-emitter which give real time medical information to incoming emergency medical professionals;
a membrane located between the syrette and a skin surface, the membrane being capable of penetration by the syrette; and
wherein the vital sign sensor is a blood pressure sensor, a pulse rate sensor, or a pulse oximetry sensor.

### Claim 14 (depends on 13)

The device of claim 13 wherein the housing is between 1 and 1.5 inches high and has an area of 2 square inches.
